Gene description for Ilf2
Gene name interleukin enhancer binding factor 2
Gene symbol Ilf2
Other names/aliases 6230405A16Rik
TEG-267
Tex261
Tex267
Species Mus musculus
 Database cross references - Ilf2
ExoCarta ExoCarta_67781
Vesiclepedia VP_67781
Entrez Gene 67781
UniProt Q9CXY6  
 Ilf2 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ilf2
Molecular Function
    DNA binding GO:0003677 ISO
    double-stranded RNA binding GO:0003725 ISO
    RNA binding GO:0003723 IEA
    poly(A) RNA binding GO:0044822 ISO
    ATP binding GO:0005524 IEA
    transferase activity GO:0016740 IEA
Biological Process
    positive regulation of transcription, DNA-templated GO:0045893 ISO
    immune response GO:0006955 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    transcription, DNA-templated GO:0006351 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    ribonucleoprotein complex GO:0030529 ISO
    nucleolus GO:0005730 ISO
    membrane GO:0016020 ISO
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Ilf2 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ilf2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RUTBC1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which Ilf2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here