Gene description for USP22
Gene name	ubiquitin specific peptidase 22
Gene symbol	USP22
Other names/aliases	USP3L
Species	Homo sapiens
Database cross references - USP22
ExoCarta	ExoCarta_23326
Entrez Gene	23326
HGNC	12621
MIM	612116
UniProt	Q9UPT9
USP22 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723

Gene ontology annotations for USP22

Molecular Function     zinc ion binding GO:0008270 IEA     cysteine-type endopeptidase activity GO:0004197 IBA     protein binding GO:0005515 IPI     ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 IMP     H4 histone acetyltransferase activity GO:0010485 IDA     transcription coactivator activity GO:0003713 IDA     ubiquitin-specific protease activity GO:0004843 IMP     enzyme binding GO:0019899 IPI Biological Process     histone ubiquitination GO:0016574 IDA     chromatin organization GO:0006325 TAS     histone deubiquitination GO:0016578 IDA     embryo development GO:0009790 NAS     transcription, DNA-templated GO:0006351 IEA     positive regulation of mitotic cell cycle GO:0045931 IMP     protein deubiquitination GO:0016579 IDA     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IBA     positive regulation of transcription, DNA-templated GO:0045893 IMP     cell cycle GO:0007049 IEA     regulation of proteasomal protein catabolic process GO:0061136 IBA     histone H4 acetylation GO:0043967 IDA Subcellular Localization     SAGA-type complex GO:0070461 IDA     SAGA complex GO:0000124 IDA