Gene description for ATXN7L3B
Gene name ataxin 7-like 3B
Gene symbol ATXN7L3B
Other names/aliases lnc-SCA7
Species Homo sapiens
 Database cross references - ATXN7L3B
ExoCarta ExoCarta_552889
Vesiclepedia VP_552889
Entrez Gene 552889
HGNC 37931
MIM 615579
UniProt Q96GX2  
 ATXN7L3B identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ATXN7L3B
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    regulation of gene expression GO:0010468 IBA
    regulation of gene expression GO:0010468 IEP
Subcellular Localization
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified ATXN7L3B in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ATXN7L3B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDC25A  
Affinity Capture-MS Homo sapiens
2 PTPN5  
Affinity Capture-MS Homo sapiens
3 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
4 ENY2 56943
Affinity Capture-MS Homo sapiens
5 EGFR 1956
Affinity Capture-MS Homo sapiens
6 PTP4A2 8073
Affinity Capture-MS Homo sapiens
7 USP22 23326
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ATXN7L3B is involved
No pathways found





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