Gene description for SUPT20H
Gene name suppressor of Ty 20 homolog (S. cerevisiae)
Gene symbol SUPT20H
Other names/aliases C13
C13orf19
FAM48A
FP757
P38IP
SPT20
Species Homo sapiens
 Database cross references - SUPT20H
ExoCarta ExoCarta_55578
Vesiclepedia VP_55578
Entrez Gene 55578
HGNC 20596
MIM 613417
UniProt Q8NEM7  
 SUPT20H identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for SUPT20H
Molecular Function
    transcription cofactor activity GO:0003712 IEA
    protein binding GO:0005515 IPI
Biological Process
    autophagy GO:0006914 IEA
    chromatin organization GO:0006325 TAS
    positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter GO:0035948 IEA
    gastrulation GO:0007369 IEA
Subcellular Localization
    SAGA complex GO:0000124 IEA
    nucleolus GO:0005730 IDA
    SAGA-type complex GO:0070461 IDA
 Experiment description of studies that identified SUPT20H in exosomes
1
Experiment ID 191
MISEV standards
✘ EV Biophysical techniques
✔
Alix|CD81|CD9
EV Enriched markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SUPT20H
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SUPT20H is involved
PathwayEvidenceSource
HATs acetylate histones TAS Reactome





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