Gene description for TAF9
Gene name TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
Gene symbol TAF9
Other names/aliases MGC:5067
STAF31/32
TAF2G
TAFII-31
TAFII-32
TAFII31
TAFII32
TAFIID32
Species Homo sapiens
 Database cross references - TAF9
ExoCarta ExoCarta_6880
Vesiclepedia VP_6880
Entrez Gene 6880
HGNC 11542
MIM 600822
UniProt Q16594  
 TAF9 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for TAF9
Molecular Function
    protein heterodimerization activity GO:0046982 IEA
    histone acetyltransferase activity GO:0004402 IDA
    activating transcription factor binding GO:0033613 IPI
    transcription regulatory region DNA binding GO:0044212 IDA
    transcription coactivator activity GO:0003713 IMP
    protein binding GO:0005515 IPI
    p53 binding GO:0002039 IPI
    C2H2 zinc finger domain binding GO:0070742 IPI
    DNA binding GO:0003677 IDA
Biological Process
    viral process GO:0016032 TAS
    response to interleukin-1 GO:0070555 IMP
    positive regulation of cell growth GO:0030307 IMP
    negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:1902166 IC
    cellular response to DNA damage stimulus GO:0006974 IC
    negative regulation of apoptotic process GO:0043066 IMP
    transcription elongation from RNA polymerase II promoter GO:0006368 TAS
    positive regulation of response to cytokine stimulus GO:0060760 IMP
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
    chromatin organization GO:0006325 TAS
    histone H3 acetylation GO:0043966 IDA
    protein stabilization GO:0050821 IDA
    transcription from RNA polymerase II promoter GO:0006366 TAS
    negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 IDA
    transcription initiation from RNA polymerase II promoter GO:0006367 TAS
    gene expression GO:0010467 TAS
Subcellular Localization
    pre-snoRNP complex GO:0070761 IDA
    nucleoplasm GO:0005654 TAS
    transcription factor TFIID complex GO:0005669 IDA
    PCAF complex GO:0000125 IDA
    transcription factor TFTC complex GO:0033276 IDA
    MLL1 complex GO:0071339 IDA
    STAGA complex GO:0030914 IDA
 Experiment description of studies that identified TAF9 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TAF9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DKFZP564O0523  
Two-hybrid Homo sapiens
2 TAF5  
Invivo Homo sapiens
Invitro Homo sapiens
3 TBP  
Co-purification Homo sapiens
4 MYC  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-purification Homo sapiens
5 PCAF  
Affinity Capture-Western Homo sapiens
6 DRAP1 10589
Two-hybrid Homo sapiens
7 EEF1A1 1915
Two-hybrid Homo sapiens
8 TP53 7157
Invitro Homo sapiens
9 RPS14 6208
Two-hybrid Homo sapiens
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