Gene description for HS1BP3
Gene name HCLS1 binding protein 3
Gene symbol HS1BP3
Other names/aliases ETM2
HS1-BP3
Species Homo sapiens
 Database cross references - HS1BP3
ExoCarta ExoCarta_64342
Vesiclepedia VP_64342
Entrez Gene 64342
HGNC 24979
MIM 609359
UniProt Q53T59  
 HS1BP3 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for HS1BP3
Molecular Function
    protein binding GO:0005515 IPI
    phosphatidylinositol binding GO:0035091 IEA
Biological Process
    regulation of apoptotic process GO:0042981 IMP
Subcellular Localization
    mitochondrion GO:0005739 IDA
    endoplasmic reticulum GO:0005783 IDA
 Experiment description of studies that identified HS1BP3 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for HS1BP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DMXL2  
Affinity Capture-MS Homo sapiens
2 ANTXR2 118429
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 MECP2 4204
Affinity Capture-MS Homo sapiens
4 BPIFA1 51297
Affinity Capture-MS Homo sapiens
5 NARF 26502
Affinity Capture-MS Homo sapiens
6 TMED3 23423
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 SUPT20H 55578
Affinity Capture-MS Homo sapiens
8 HBS1L 10767
Affinity Capture-MS Homo sapiens
9 NAA38  
Co-fractionation Homo sapiens
10 RAB7A 7879
Proximity Label-MS Homo sapiens
11 CTU1 90353
Affinity Capture-MS Homo sapiens
12 C20orf194  
Affinity Capture-MS Homo sapiens
13 IREB2 3658
Affinity Capture-MS Homo sapiens
14 TAF5L  
Affinity Capture-MS Homo sapiens
15 LONRF2  
Affinity Capture-MS Homo sapiens
16 DSTYK 25778
Affinity Capture-MS Homo sapiens
17 ZDHHC17 23390
Two-hybrid Homo sapiens
18 IFI30  
Co-fractionation Homo sapiens
19 TCP10L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 MPO 4353
Affinity Capture-MS Homo sapiens
21 TYW1  
Affinity Capture-MS Homo sapiens
22 CDK5RAP1  
Affinity Capture-MS Homo sapiens
23 SUPT7L  
Affinity Capture-MS Homo sapiens
24 TAF9B  
Affinity Capture-MS Homo sapiens
25 RAD50 10111
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 HTT 3064
Affinity Capture-MS Homo sapiens
27 CTSG 1511
Affinity Capture-MS Homo sapiens
28 PDXDC1 23042
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 ABTB2 25841
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 RWDD2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 ACOX1 51
Affinity Capture-MS Homo sapiens
32 VCP 7415
Affinity Capture-MS Homo sapiens
33 SELENBP1 8991
Affinity Capture-MS Homo sapiens
34 USP5 8078
Co-fractionation Homo sapiens
35 LIG1 3978
Co-fractionation Homo sapiens
36 TCHH  
Affinity Capture-MS Homo sapiens
37 SPATA20  
Affinity Capture-MS Homo sapiens
38 PRPS1 5631
Affinity Capture-MS Homo sapiens
39 TADA2B  
Affinity Capture-MS Homo sapiens
40 DYNC2H1 79659
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which HS1BP3 is involved
No pathways found





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