Gene description for NARF
Gene name nuclear prelamin A recognition factor
Gene symbol NARF
Other names/aliases IOP2
Species Homo sapiens
 Database cross references - NARF
ExoCarta ExoCarta_26502
Entrez Gene 26502
HGNC 29916
MIM 605349
UniProt Q9UHQ1  
 NARF identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for NARF
Molecular Function
    lamin binding GO:0005521 IPI
    NADH dehydrogenase activity GO:0003954 IBA
    iron-sulfur cluster binding GO:0051536 IBA
Biological Process
    iron-sulfur cluster assembly GO:0016226 IBA
Subcellular Localization
    nuclear lamina GO:0005652 TAS
    cytosol GO:0005829 IBA
    nuclear lumen GO:0031981 IDA
    nucleus GO:0005634 IDA
    lamin filament GO:0005638 IDA
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified NARF in exosomes
Experiment ID 235
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for NARF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LMNA 4000
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NARF is involved
No pathways found

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