Experiment description of studies that identified PREPL in sEVs

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for PREPL

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SLIRP 81892 Affinity Capture-MS Homo sapiens 2 UQCRFS1 7386 Affinity Capture-MS Homo sapiens 3 COIL   Two-hybrid Homo sapiens 4 TRUB2   Proximity Label-MS Homo sapiens 5 MTG2   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 CHCHD1   Proximity Label-MS Homo sapiens 7 MRPL10 124995 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 C4orf26   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 RPUSD4 84881 Proximity Label-MS Homo sapiens 10 UNKL   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 MTRF1   Proximity Label-MS Homo sapiens 12 CRYZ 1429 Affinity Capture-MS Homo sapiens 13 PMPCA 23203 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 SDHB 6390 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 YARS2   Affinity Capture-MS Homo sapiens 16 HINT2 84681 Proximity Label-MS Homo sapiens 17 MRPS24 64951 Affinity Capture-MS Homo sapiens 18 MRPL12 6182 Affinity Capture-MS Homo sapiens 19 FTSJ2 29960 Affinity Capture-MS Homo sapiens 20 MDH2 4191 Proximity Label-MS Homo sapiens 21 MRRF   Proximity Label-MS Homo sapiens 22 EXD2   Proximity Label-MS Homo sapiens 23 PMPCB 9512 Proximity Label-MS Homo sapiens 24 PREPL 9581 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 METTL2A   Affinity Capture-MS Homo sapiens 26 USP22 23326 Affinity Capture-MS Homo sapiens 27 RGS4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 MRPS25 64432 Affinity Capture-MS Homo sapiens 29 C6orf203   Proximity Label-MS Homo sapiens 30 MRPS26 64949 Proximity Label-MS Homo sapiens 31 PARK2   Affinity Capture-MS Homo sapiens 32 MRPS34 65993 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 TUFM 7284 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 DHRS2 10202 Affinity Capture-MS Homo sapiens 35 HSCB 150274 Proximity Label-MS Homo sapiens 36 DHRS4L2   Affinity Capture-MS Homo sapiens 37 PDHX 8050 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 C9orf170   Affinity Capture-MS Homo sapiens 39 TEX30   Affinity Capture-MS Homo sapiens 40 MRPL11 65003 Proximity Label-MS Homo sapiens 41 MTRF1L   Proximity Label-MS Homo sapiens 42 COX4I1 1327 Proximity Label-MS Homo sapiens 43 MRPL41 64975 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 44 MRM1   Affinity Capture-MS Homo sapiens 45 OTC 5009 Proximity Label-MS Homo sapiens 46 RARS2   Affinity Capture-MS Homo sapiens 47 MRPL21 219927 Affinity Capture-MS Homo sapiens 48 NIPSNAP3A   Affinity Capture-MS Homo sapiens 49 MRPS12   Proximity Label-MS Homo sapiens 50 MTIF2 4528 Proximity Label-MS Homo sapiens 51 METTL20   Affinity Capture-MS Homo sapiens 52 NR3C1 2908 Proximity Label-MS Homo sapiens 53 FAHD1 81889 Affinity Capture-MS Homo sapiens 54 BEX1   Affinity Capture-MS Homo sapiens 55 C12orf65   Proximity Label-MS Homo sapiens 56 MTG1   Proximity Label-MS Homo sapiens 57 APEH 327 Co-fractionation Homo sapiens 58 ACAD9 28976 Proximity Label-MS Homo sapiens 59 MRPS17 51373 Affinity Capture-MS Homo sapiens 60 PFDN5 5204 Affinity Capture-MS Homo sapiens 61 MCUR1 63933 Proximity Label-MS Homo sapiens 62 AK4 205 Affinity Capture-MS Homo sapiens 63 CLPP 8192 Proximity Label-MS Homo sapiens 64 CS 1431 Proximity Label-MS Homo sapiens Proximity Label-MS Homo sapiens 65 GOT2 2806 Affinity Capture-MS Homo sapiens 66 TSFM 10102 Proximity Label-MS Homo sapiens 67 AUH 549 Proximity Label-MS Homo sapiens 68 LIG3 3980 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 MCAT 27349 Affinity Capture-MS Homo sapiens 70 ACAA2 10449 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 71 PDHA1 5160 Proximity Label-MS Homo sapiens 72 PDDC1 347862 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 73 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 74 COX8A   Proximity Label-MS Homo sapiens 75 C21orf33   Proximity Label-MS Homo sapiens 76 SSBP1 6742 Proximity Label-MS Homo sapiens 77 GFM1 85476 Proximity Label-MS Homo sapiens 78 AARS2   Proximity Label-MS Homo sapiens 79 ARHGAP36   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 RPUSD3   Proximity Label-MS Homo sapiens 81 LBX2   Affinity Capture-MS Homo sapiens 82 C1QBP 708 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 83 LDLR 3949 Negative Genetic Homo sapiens 84 METTL17   Proximity Label-MS Homo sapiens 85 YBEY   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 86 NDUFS6   Affinity Capture-MS Homo sapiens 87 TTC39B 158219 Affinity Capture-MS Homo sapiens 88 NDUFS7 374291 Affinity Capture-MS Homo sapiens View the network

Pathways in which PREPL is involved

No pathways found