Gene description for MRPL41
Gene name mitochondrial ribosomal protein L41
Gene symbol MRPL41
Other names/aliases BMRP
MRP-L27
MRPL27
PIG3
RPML27
Species Homo sapiens
 Database cross references - MRPL41
ExoCarta ExoCarta_64975
Vesiclepedia VP_64975
Entrez Gene 64975
HGNC 14492
MIM 611846
UniProt Q8IXM3  
 MRPL41 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MRPL41
Molecular Function
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    protein binding GO:0005515 IPI
Biological Process
    translation GO:0006412 IBA
    translation GO:0006412 IDA
    apoptotic process GO:0006915 IEA
    mitochondrial translation GO:0032543 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial large ribosomal subunit GO:0005762 IBA
    mitochondrial large ribosomal subunit GO:0005762 IDA
    mitochondrial large ribosomal subunit GO:0005762 NAS
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified MRPL41 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MRPL41
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 RIT1 6016
Negative Genetic Homo sapiens
3 SLIRP 81892
Proximity Label-MS Homo sapiens
4 H1FNT  
Affinity Capture-MS Homo sapiens
5 MRPL48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 COX15 1355
Proximity Label-MS Homo sapiens
7 MRPL17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 MRPL34  
Affinity Capture-MS Homo sapiens
9 TRUB2  
Proximity Label-MS Homo sapiens
10 MTG2  
Proximity Label-MS Homo sapiens
11 NGRN  
Proximity Label-MS Homo sapiens
12 RPL10 6134
Affinity Capture-MS Homo sapiens
13 CHCHD1  
Proximity Label-MS Homo sapiens
14 MRPL37 51253
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
15 MRPL27 51264
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 MRPL50 54534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 TRIM55  
Two-hybrid Homo sapiens
18 MRPL52  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
19 RPUSD4 84881
Proximity Label-MS Homo sapiens
20 MRPL49 740
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 DNAJC15  
Proximity Label-MS Homo sapiens
22 MTRF1  
Proximity Label-MS Homo sapiens
23 GFM2 84340
Proximity Label-MS Homo sapiens
24 CCDC90B  
Proximity Label-MS Homo sapiens
25 LRPPRC 10128
Proximity Label-MS Homo sapiens
26 KIAA1429 25962
Affinity Capture-MS Homo sapiens
27 MRPL20 55052
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 MCU 90550
Proximity Label-MS Homo sapiens
29 OGDH 4967
Co-fractionation Homo sapiens
30 TFAM 7019
Proximity Label-MS Homo sapiens
31 MRPL15 29088
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 PMPCA 23203
Proximity Label-MS Homo sapiens
33 C8orf82  
Proximity Label-MS Homo sapiens
34 MRPL23 6150
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 SMYD3 64754
Affinity Capture-MS Homo sapiens
36 HINT2 84681
Proximity Label-MS Homo sapiens
37 MRPL12 6182
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 ABCD3 5825
Co-fractionation Homo sapiens
39 NPM1 4869
Affinity Capture-MS Homo sapiens
40 Rfx5  
Affinity Capture-MS Mus musculus
41 RPS9 6203
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
42 MRPS26 64949
Proximity Label-MS Homo sapiens
43 MALSU1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 EXD2  
Proximity Label-MS Homo sapiens
45 MRPL39 54148
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
47 MECP2 4204
Affinity Capture-MS Homo sapiens
48 BTRC 8945
Affinity Capture-MS Homo sapiens
49 PMPCB 9512
Proximity Label-MS Homo sapiens
50 MRPL4 51073
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 FASTKD2  
Proximity Label-MS Homo sapiens
52 KLF15  
Affinity Capture-MS Homo sapiens
53 VWA8 23078
Proximity Label-MS Homo sapiens
54 MRPL47 57129
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 RPL19 6143
Affinity Capture-MS Homo sapiens
56 MTERF3  
Proximity Label-MS Homo sapiens
57 MDH2 4191
Proximity Label-MS Homo sapiens
58 MRPS30 10884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 E2F4  
Affinity Capture-MS Homo sapiens
60 MRPL13  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 MRPL57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 MRPL32 64983
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 C6orf203  
Proximity Label-MS Homo sapiens
64 HNRNPA0 10949
Co-fractionation Homo sapiens
65 RC3H2  
Affinity Capture-MS Homo sapiens
66 FASTKD5  
Proximity Label-MS Homo sapiens
67 MRPL45 84311
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 MRPL30  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 MRPS34 65993
Affinity Capture-MS Homo sapiens
70 NBR1 4077
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 SRSF3 6428
Affinity Capture-MS Homo sapiens
72 NONO 4841
Co-fractionation Homo sapiens
73 TUFM 7284
Proximity Label-MS Homo sapiens
74 HSCB 150274
Proximity Label-MS Homo sapiens
75 FUBP1 8880
Co-fractionation Homo sapiens
76 MRPL51 51258
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
77 CCDC109B 55013
Proximity Label-MS Homo sapiens
78 EXOSC5 56915
Affinity Capture-MS Homo sapiens
79 TBRG4 9238
Proximity Label-MS Homo sapiens
80 MRPL3  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 Bag2  
Affinity Capture-MS Mus musculus
82 AARS2  
Proximity Label-MS Homo sapiens
83 MRPL11 65003
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 MTRF1L  
Proximity Label-MS Homo sapiens
85 TMEM70  
Proximity Label-MS Homo sapiens
86 TRIM63  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
87 Slain1  
Affinity Capture-MS Mus musculus
88 MRPL2 51069
Affinity Capture-MS Homo sapiens
89 COX4I1 1327
Proximity Label-MS Homo sapiens
90 NPM3 10360
Affinity Capture-MS Homo sapiens
91 ANLN 54443
Affinity Capture-MS Homo sapiens
92 MRPL14 64928
Affinity Capture-MS Homo sapiens
93 MRPL44  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 MRPL40 64976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 MRPL21 219927
Affinity Capture-MS Homo sapiens
96 MRRF  
Proximity Label-MS Homo sapiens
97 ABT1 29777
Affinity Capture-MS Homo sapiens
98 MRPS12  
Proximity Label-MS Homo sapiens
99 MRPL10 124995
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 MTIF2 4528
Proximity Label-MS Homo sapiens
101 MRPL24  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 MRPL35  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 YBX1 4904
Affinity Capture-MS Homo sapiens
104 MTIF3  
Proximity Label-MS Homo sapiens
105 RPL35 11224
Affinity Capture-MS Homo sapiens
106 TMED8 283578
Two-hybrid Homo sapiens
107 MRPL9 65005
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 MRPL16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 SURF6  
Affinity Capture-MS Homo sapiens
110 NR3C1 2908
Proximity Label-MS Homo sapiens
111 FAHD1 81889
Affinity Capture-MS Homo sapiens
112 WIPI1 55062
Affinity Capture-MS Homo sapiens
113 GADD45GIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 C17orf80 55028
Proximity Label-MS Homo sapiens
115 CAND1 55832
Affinity Capture-MS Homo sapiens
116 AURKB 9212
Affinity Capture-MS Homo sapiens
117 C12orf65  
Proximity Label-MS Homo sapiens
118 MYCN  
Affinity Capture-MS Homo sapiens
119 TACO1  
Proximity Label-MS Homo sapiens
120 MTG1  
Proximity Label-MS Homo sapiens
121 MYC  
Affinity Capture-MS Homo sapiens
122 NIN 51199
Proximity Label-MS Homo sapiens
123 TSFM 10102
Proximity Label-MS Homo sapiens
124 ACAD9 28976
Proximity Label-MS Homo sapiens
125 DDRGK1 65992
Affinity Capture-MS Homo sapiens
126 PLP2 5355
Co-fractionation Homo sapiens
127 MRPL38  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 TSR1 55720
Co-fractionation Homo sapiens
129 METTL15  
Proximity Label-MS Homo sapiens
130 RBMS2 5939
Affinity Capture-MS Homo sapiens
131 SOX2  
Affinity Capture-MS Homo sapiens
132 RPL13 6137
Affinity Capture-MS Homo sapiens
133 CLPP 8192
Proximity Label-MS Homo sapiens
134 CS 1431
Proximity Label-MS Homo sapiens
135 MRPL42  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
136 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
137 RC3H1 149041
Affinity Capture-MS Homo sapiens
138 AUH 549
Proximity Label-MS Homo sapiens
139 ILF3 3609
Co-fractionation Homo sapiens
140 MRPL22  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 FBXL6  
Affinity Capture-MS Homo sapiens
142 TP53 7157
Affinity Capture-MS Homo sapiens
143 ICT1 3396
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 MRPS28  
Co-fractionation Homo sapiens
145 APOBEC3D  
Affinity Capture-MS Homo sapiens
146 RPS8 6202
Affinity Capture-MS Homo sapiens
147 MRPL53  
Affinity Capture-MS Homo sapiens
148 FAM3C 10447
Co-fractionation Homo sapiens
149 PDHA1 5160
Proximity Label-MS Homo sapiens
150 MRPL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 C21orf33  
Proximity Label-MS Homo sapiens
152 MRPL18 29074
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 SSBP1 6742
Proximity Label-MS Homo sapiens
154 UFL1 23376
Affinity Capture-MS Homo sapiens
155 FASTKD3  
Proximity Label-MS Homo sapiens
156 PREPL 9581
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 GFM1 85476
Proximity Label-MS Homo sapiens
158 HNRNPL 3191
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
159 TEFM  
Proximity Label-MS Homo sapiens
160 MRPL46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 MRPL19 9801
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 C14orf169  
Affinity Capture-MS Homo sapiens
163 RPUSD3  
Proximity Label-MS Homo sapiens
164 GRSF1 2926
Proximity Label-MS Homo sapiens
165 C1QBP 708
Proximity Label-MS Homo sapiens
166 MRPL55  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 METTL17  
Proximity Label-MS Homo sapiens
168 MRPL28 10573
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 MRPS18A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 MRPS9 64965
Co-fractionation Homo sapiens
View the network image/svg+xml



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