Experiment description of studies that identified TMED8 in exosomes

1 Experiment ID 231 MISEV standards ✘ Biophysical techniques ✔ Alix|CD63|CD9 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Lipids Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 232 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 233 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for TMED8

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MRPL41 64975 Two-hybrid Homo sapiens 2 AMIGO2   Two-hybrid Homo sapiens 3 UNC50   Two-hybrid Homo sapiens 4 ZDHHC16   Two-hybrid Homo sapiens 5 C10orf67   Two-hybrid Homo sapiens 6 TMEM136   Affinity Capture-MS Homo sapiens 7 TRAM1L1   Two-hybrid Homo sapiens 8 FUNDC1   Affinity Capture-MS Homo sapiens 9 TMEM218   Two-hybrid Homo sapiens 10 CMTM5   Two-hybrid Homo sapiens 11 HIST1H4G 8369 Two-hybrid Homo sapiens 12 CD8B 926 Affinity Capture-MS Homo sapiens 13 TMEM254   Two-hybrid Homo sapiens 14 XPO1 7514 Affinity Capture-MS Homo sapiens 15 MDK 4192 Two-hybrid Homo sapiens 16 ATE1 11101 Affinity Capture-MS Homo sapiens 17 FZD10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 MTIF3   Two-hybrid Homo sapiens 19 P2RX1 5023 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 CYB561D1   Two-hybrid Homo sapiens 21 GALR3   Affinity Capture-MS Homo sapiens 22 RAP1GDS1 5910 Affinity Capture-MS Homo sapiens 23 FAM96A   Two-hybrid Homo sapiens 24 STX8 9482 Two-hybrid Homo sapiens 25 TSEN2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 TMEM115 11070 Two-hybrid Homo sapiens 27 NDUFA12 55967 Two-hybrid Homo sapiens 28 ARL6IP1 23204 Two-hybrid Homo sapiens 29 TMEM121   Two-hybrid Homo sapiens 30 PTGER3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 AVPR1B   Affinity Capture-MS Homo sapiens 32 SUSD3 203328 Two-hybrid Homo sapiens 33 MMGT1 93380 Two-hybrid Homo sapiens 34 SERP2   Two-hybrid Homo sapiens 35 ADTRP   Two-hybrid Homo sapiens 36 KCNJ10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 SEC61B 10952 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 APOL2 23780 Two-hybrid Homo sapiens 39 SERBP1 26135 Affinity Capture-MS Homo sapiens 40 MRPS18B 28973 Two-hybrid Homo sapiens 41 RAB7A 7879 Proximity Label-MS Homo sapiens 42 GPR34   Affinity Capture-MS Homo sapiens 43 SMAD2 4087 Affinity Capture-MS Homo sapiens 44 EI24   Two-hybrid Homo sapiens 45 SSR1 6745 Proximity Label-MS Homo sapiens 46 DGAT2L6   Two-hybrid Homo sapiens 47 SEC62 7095 Proximity Label-MS Homo sapiens 48 ELOVL5 60481 Proximity Label-MS Homo sapiens 49 GPR183   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 LRRTM3   Affinity Capture-MS Homo sapiens 51 REEP6   Two-hybrid Homo sapiens 52 DEFB129   Two-hybrid Homo sapiens 53 DERL1 79139 Two-hybrid Homo sapiens 54 MAFB   Affinity Capture-MS Homo sapiens View the network

Pathways in which TMED8 is involved

No pathways found