Gene description for HIST1H4G
Gene name
histone cluster 1, H4g
Gene symbol
HIST1H4G
Other names/aliases
H4/l H4FL
Species
Homo sapiens
Database cross references - HIST1H4G
ExoCarta
ExoCarta_8369
Vesiclepedia
VP_8369
Entrez Gene
8369
HGNC
4792
MIM
602832
UniProt
Q99525
HIST1H4G identified in exosomes derived from the following tissue/cell type
Bladder cancer cells
20224111
Hepatocellular carcinoma cells
26054723
Gene ontology annotations for HIST1H4G
Experiment description of studies that identified HIST1H4G in exosomes
1
Experiment ID
76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20224111
Organism
Homo sapiens
Experiment description
Proteomics analysis of bladder cancer exosomes.
Authors
"Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name
MCP
Publication year
2010
Sample
Bladder cancer cells
Sample name
HT1376
Isolation/purification methods
Differential centrifugation Sucrose density gradient
Flotation density
1.10-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [MALDI TOF/TOF] Western blotting FACS
2
Experiment ID
235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
Protein-protein interactions for HIST1H4G
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
H2AFZ
3015
Affinity Capture-Western
Homo sapiens
2
TMED8
283578
Two-hybrid
Homo sapiens
3
AGTRAP
57085
Two-hybrid
Homo sapiens
4
APOC1
Two-hybrid
Homo sapiens
5
HIST1H2BL
8340
Cross-Linking-MS (XL-MS)
Homo sapiens
6
VRK1
7443
Affinity Capture-MS
Homo sapiens
7
C2orf47
Two-hybrid
Homo sapiens
8
MYCN
Affinity Capture-MS
Homo sapiens
9
CIDEB
Two-hybrid
Homo sapiens
10
HIST1H2BK
85236
Cross-Linking-MS (XL-MS)
Homo sapiens
11
KIF20A
10112
Affinity Capture-MS
Homo sapiens
12
CHMP4B
128866
Affinity Capture-MS
Homo sapiens
13
PRC1
9055
Affinity Capture-MS
Homo sapiens
14
HIST1H2BD
3017
Cross-Linking-MS (XL-MS)
Homo sapiens
15
HMGN1
Affinity Capture-MS
Homo sapiens
16
KIF23
9493
Affinity Capture-MS
Homo sapiens
17
FGF14
Two-hybrid
Homo sapiens
18
ANLN
54443
Affinity Capture-MS
Homo sapiens
19
HIST1H4A
8359
Cross-Linking-MS (XL-MS)
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
20
HIST2H2BE
8349
Cross-Linking-MS (XL-MS)
Homo sapiens
21
ECT2
1894
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which HIST1H4G is involved
No pathways found