Gene description for ANLN
Gene name anillin, actin binding protein
Gene symbol ANLN
Other names/aliases FSGS8
Scraps
scra
Species Homo sapiens
 Database cross references - ANLN
ExoCarta ExoCarta_54443
Entrez Gene 54443
HGNC 14082
MIM 616027
UniProt Q9NQW6  
 ANLN identified in exosomes derived from the following tissue/cell type
Melanoma cells 25950383    
Melanoma cells 25950383    
 Gene ontology annotations for ANLN
Molecular Function
    protein binding GO:0005515 IPI
    actin binding GO:0003779 IDA
Biological Process
    mitotic nuclear division GO:0007067 IEA
    glomerular visceral epithelial cell migration GO:0090521 IMP
    mitotic cytokinesis GO:0000281 IDA
    regulation of exit from mitosis GO:0007096 TAS
    septin ring assembly GO:0000921 TAS
    hematopoietic progenitor cell differentiation GO:0002244 IEA
Subcellular Localization
    actomyosin contractile ring GO:0005826 IDA
    actin cytoskeleton GO:0015629 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified ANLN in exosomes
1
Experiment ID 258
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
FLOT1|CD81
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 260
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
FLOT1|CD81
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for ANLN
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEPT7 989
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which ANLN is involved
No pathways found





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