Gene description for STAG3
Gene name stromal antigen 3
Gene symbol STAG3
Other names/aliases -
Species Homo sapiens
 Database cross references - STAG3
ExoCarta ExoCarta_10734
Entrez Gene 10734
HGNC 11356
MIM 608489
UniProt Q9UJ98  
 STAG3 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for STAG3
Biological Process
    synaptonemal complex assembly GO:0007130 TAS
Subcellular Localization
    meiotic cohesin complex GO:0030893 IDA
    nucleolus GO:0005730 IDA
    extracellular space GO:0005615 IDA
    synaptonemal complex GO:0000795 TAS
    nucleus GO:0005634 IDA
    chromosome, centromeric region GO:0000775 IEA
 Experiment description of studies that identified STAG3 in exosomes
1
Experiment ID 224
ISEV standards
✔
EM|AFM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✔
GOLGA2
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for STAG3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which STAG3 is involved
PathwayEvidenceSource
Meiotic synapsis TAS Reactome





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