Gene description for SMC1A
Gene name structural maintenance of chromosomes 1A
Gene symbol SMC1A
Other names/aliases CDLS2
DXS423E
SB1.8
SMC1
SMC1L1
SMC1alpha
SMCB
Species Homo sapiens
 Database cross references - SMC1A
ExoCarta ExoCarta_8243
Vesiclepedia VP_8243
Entrez Gene 8243
HGNC 11111
MIM 300040
UniProt Q14683  
 SMC1A identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for SMC1A
Molecular Function
    DNA binding GO:0003677 IBA
    chromatin binding GO:0003682 IDA
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
    mediator complex binding GO:0036033 IEA
    protein heterodimerization activity GO:0046982 IPI
Biological Process
    mitotic sister chromatid segregation GO:0000070 TAS
    DNA repair GO:0006281 TAS
    sister chromatid cohesion GO:0007062 IBA
    sister chromatid cohesion GO:0007062 IMP
    mitotic sister chromatid cohesion GO:0007064 TAS
    response to radiation GO:0009314 IEP
    establishment of mitotic sister chromatid cohesion GO:0034087 NAS
    establishment of meiotic sister chromatid cohesion GO:0034089 NAS
    somatic stem cell population maintenance GO:0035019 IEA
    cell division GO:0051301 IEA
    meiotic cell cycle GO:0051321 ISS
    response to DNA damage checkpoint signaling GO:0072423 IDA
    mitotic spindle assembly GO:0090307 IMP
Subcellular Localization
    chromosome, centromeric region GO:0000775 TAS
    kinetochore GO:0000776 IDA
    condensed nuclear chromosome GO:0000794 TAS
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    chromosome GO:0005694 TAS
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    cohesin complex GO:0008278 IDA
    cohesin complex GO:0008278 TAS
    nuclear matrix GO:0016363 IDA
    mitotic cohesin complex GO:0030892 IPI
    mitotic cohesin complex GO:0030892 ISS
    meiotic cohesin complex GO:0030893 IBA
    meiotic cohesin complex GO:0030893 IDA
    meiotic cohesin complex GO:0030893 NAS
    mitotic spindle pole GO:0097431 IDA
 Experiment description of studies that identified SMC1A in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
20
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SMC1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDCA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Synthetic Rescue Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 REC8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 SLFN11 91607
Affinity Capture-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 MCM7 4176
Co-fractionation Homo sapiens
6 UBE2H 7328
Affinity Capture-MS Homo sapiens
7 SMC3 9126
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
8 HMGN5 79366
Affinity Capture-MS Homo sapiens
9 KIAA1191  
Affinity Capture-MS Homo sapiens
10 NUF2  
Affinity Capture-MS Homo sapiens
11 SNX3 8724
Affinity Capture-MS Homo sapiens
12 ELF1 1997
Proximity Label-MS Homo sapiens
13 COIL  
Proximity Label-MS Homo sapiens
14 PAXIP1  
Affinity Capture-MS Homo sapiens
15 MSH6 2956
Reconstituted Complex Homo sapiens
16 USP13  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 PPIE 10450
Affinity Capture-MS Homo sapiens
18 KIF13A 63971
Co-fractionation Homo sapiens
19 RPA2 6118
Affinity Capture-MS Homo sapiens
20 NR3C1 2908
Affinity Capture-MS Homo sapiens
21 SUB1 10923
Affinity Capture-MS Homo sapiens
22 EN1  
Proximity Label-MS Homo sapiens
23 BRCA1 672
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
24 HLTF  
Affinity Capture-MS Homo sapiens
25 C9orf78 51759
Affinity Capture-MS Homo sapiens
26 KLF12  
Proximity Label-MS Homo sapiens
27 HSP90AB1 3326
Cross-Linking-MS (XL-MS) Homo sapiens
28 ATM 472
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
29 MRPL50 54534
Affinity Capture-MS Homo sapiens
30 SAP30 8819
Affinity Capture-MS Homo sapiens
31 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
32 SIX1  
Affinity Capture-MS Homo sapiens
33 FAM174A 345757
Affinity Capture-MS Homo sapiens
34 ANKRD28 23243
Proximity Label-MS Homo sapiens
35 SOX2  
Proximity Label-MS Homo sapiens
36 ATG4C  
Affinity Capture-MS Homo sapiens
37 PAX6  
Proximity Label-MS Homo sapiens
38 ANKRD17 26057
Cross-Linking-MS (XL-MS) Homo sapiens
39 KIAA1429 25962
Affinity Capture-MS Homo sapiens
40 ETV3  
Proximity Label-MS Homo sapiens
41 WDR76  
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
42 EMILIN1 11117
Affinity Capture-MS Homo sapiens
43 BRD4 23476
Affinity Capture-Western Homo sapiens
44 TGFB1 7040
Affinity Capture-MS Homo sapiens
45 MCM2 4171
Affinity Capture-MS Homo sapiens
46 SPAG9 9043
Affinity Capture-MS Homo sapiens
47 FBXW7  
Affinity Capture-MS Homo sapiens
48 MDC1  
Affinity Capture-Western Homo sapiens
49 H2AFY2 55506
Cross-Linking-MS (XL-MS) Homo sapiens
50 OBSL1 23363
Affinity Capture-MS Homo sapiens
51 SMC2 10592
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
52 MCM6 4175
Affinity Capture-MS Homo sapiens
53 PSMC2 5701
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 ABCE1 6059
Affinity Capture-MS Homo sapiens
55 EPS15L1 58513
Affinity Capture-MS Homo sapiens
56 Cdca5  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
57 DDI1  
Affinity Capture-MS Homo sapiens
58 EED  
Affinity Capture-MS Homo sapiens
59 FEV  
Proximity Label-MS Homo sapiens
60 LSM1 27257
Affinity Capture-MS Homo sapiens
61 ATG16L1 55054
Affinity Capture-MS Homo sapiens
62 POLR2C 5432
Proximity Label-MS Homo sapiens
63 KLHL20  
Affinity Capture-MS Homo sapiens
64 PHF1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
65 RNF126  
Affinity Capture-MS Homo sapiens
66 GANC  
Affinity Capture-MS Homo sapiens
67 SRSF6 6431
Affinity Capture-MS Homo sapiens
68 ARHGEF4  
Affinity Capture-MS Homo sapiens
69 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 RBM14 10432
Co-fractionation Homo sapiens
71 USP37  
Proximity Label-MS Homo sapiens
72 PDS5B 23047
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 NFIX 4784
Proximity Label-MS Homo sapiens
74 SMC4 10051
Co-fractionation Homo sapiens
75 ITLN1 55600
Affinity Capture-MS Homo sapiens
76 EMC9  
Affinity Capture-MS Homo sapiens
77 ANAPC2 29882
Proximity Label-MS Homo sapiens
78 KLF16  
Proximity Label-MS Homo sapiens
79 CHMP4C 92421
Affinity Capture-MS Homo sapiens
80 THRB 7068
Affinity Capture-MS Homo sapiens
81 NF2 4771
Affinity Capture-MS Homo sapiens
82 SF3A2 8175
Co-fractionation Homo sapiens
83 ATG2A  
Affinity Capture-MS Homo sapiens
84 FOXC1  
Affinity Capture-MS Homo sapiens
85 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
86 TLX3  
Proximity Label-MS Homo sapiens
87 LSM14B 149986
Affinity Capture-MS Homo sapiens
88 RB1CC1 9821
Affinity Capture-MS Homo sapiens
89 PARK2  
Affinity Capture-MS Homo sapiens
90 COPE 11316
Co-fractionation Homo sapiens
91 HMGN2 3151
Cross-Linking-MS (XL-MS) Homo sapiens
92 TEAD1  
Proximity Label-MS Homo sapiens
93 STAU1 6780
Affinity Capture-MS Homo sapiens
94 ACIN1 22985
Co-fractionation Homo sapiens
95 Smc3 13006
Affinity Capture-MS Mus musculus
96 ALPI  
Affinity Capture-MS Homo sapiens
97 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
98 CFDP1  
Affinity Capture-MS Homo sapiens
99 Rad21  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
100 LHX1  
Proximity Label-MS Homo sapiens
101 UBXN1 51035
Cross-Linking-MS (XL-MS) Homo sapiens
102 ATR  
Affinity Capture-Western Homo sapiens
103 LHX2  
Proximity Label-MS Homo sapiens
104 PDS5A 23244
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 BARD1 580
Co-purification Homo sapiens
106 TTN 7273
Cross-Linking-MS (XL-MS) Homo sapiens
107 Stag2  
Affinity Capture-MS Mus musculus
108 BPTF 2186
Affinity Capture-MS Homo sapiens
109 TEAD2  
Affinity Capture-MS Homo sapiens
110 GAPDH 2597
Cross-Linking-MS (XL-MS) Homo sapiens
111 HUWE1 10075
Affinity Capture-MS Homo sapiens
112 SMC1A 8243
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
113 HECTD1 25831
Affinity Capture-MS Homo sapiens
114 GCC1 79571
Affinity Capture-MS Homo sapiens
115 POLE  
Co-fractionation Homo sapiens
116 ATRX 546
Affinity Capture-Western Homo sapiens
117 SDF4 51150
Affinity Capture-MS Homo sapiens
118 HDAC5 10014
Affinity Capture-MS Homo sapiens
119 CAMKK2 10645
Affinity Capture-MS Homo sapiens
120 CEBPA  
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
121 STAG2 10735
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 KCTD2  
Affinity Capture-MS Homo sapiens
123 HDDC3  
Affinity Capture-MS Homo sapiens
124 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
125 USP32 84669
Affinity Capture-MS Homo sapiens
126 MGMT 4255
Affinity Capture-MS Homo sapiens
127 CD3EAP  
Proximity Label-MS Homo sapiens
128 CASP4  
Affinity Capture-MS Homo sapiens
129 SCARNA22  
Affinity Capture-RNA Homo sapiens
130 ANLN 54443
Affinity Capture-MS Homo sapiens
131 HNRNPDL 9987
Cross-Linking-MS (XL-MS) Homo sapiens
132 Sumo3  
Affinity Capture-MS Mus musculus
133 NUMA1 4926
Affinity Capture-Western Homo sapiens
134 NTRK1 4914
Affinity Capture-MS Homo sapiens
135 HSF1  
Affinity Capture-MS Homo sapiens
136 DZIP3  
Affinity Capture-MS Homo sapiens
137 FANCD2  
Affinity Capture-MS Homo sapiens
138 FOXG1  
Affinity Capture-MS Homo sapiens
139 WFDC5  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
140 SMARCAD1  
Affinity Capture-MS Homo sapiens
141 SNRPD2 6633
Cross-Linking-MS (XL-MS) Homo sapiens
142 RPL15 6138
Cross-Linking-MS (XL-MS) Homo sapiens
143 USP15 9958
Affinity Capture-MS Homo sapiens
144 MGME1  
Affinity Capture-MS Homo sapiens
145 SMARCA5 8467
Co-purification Homo sapiens
Co-fractionation Homo sapiens
146 NSMCE2  
Co-fractionation Homo sapiens
147 PRKAA2 5563
Affinity Capture-MS Homo sapiens
148 MGARP  
Affinity Capture-MS Homo sapiens
149 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 YWHAZ 7534
Affinity Capture-MS Homo sapiens
151 MECP2 4204
Affinity Capture-MS Homo sapiens
152 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
153 MAP2K2 5605
Affinity Capture-MS Homo sapiens
154 FBXO6 26270
Affinity Capture-Western Homo sapiens
155 FOXL1  
Affinity Capture-MS Homo sapiens
156 METTL21B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 PLK1 5347
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
158 POLR2A 5430
Affinity Capture-Western Homo sapiens
159 WAPAL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 CITED1 4435
Affinity Capture-MS Homo sapiens
161 RFC1 5981
Co-fractionation Homo sapiens
162 THRA  
Affinity Capture-MS Homo sapiens
163 CTCF  
Affinity Capture-Western Homo sapiens
164 CDK2 1017
Affinity Capture-MS Homo sapiens
165 RPGR  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
166 NUP43 348995
Proximity Label-MS Homo sapiens
167 MAU2  
Affinity Capture-MS Homo sapiens
168 MTUS1  
Affinity Capture-MS Homo sapiens
169 PCBP1 5093
Affinity Capture-MS Homo sapiens
170 MCM4 4173
Affinity Capture-MS Homo sapiens
171 VSIG4  
Affinity Capture-MS Homo sapiens
172 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
173 RPS13 6207
Cross-Linking-MS (XL-MS) Homo sapiens
174 EHMT2 10919
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
175 NIPBL 25836
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
176 H1F0 3005
Cross-Linking-MS (XL-MS) Homo sapiens
177 CDK20  
Affinity Capture-MS Homo sapiens
178 SNW1 22938
Affinity Capture-MS Homo sapiens
179 PARP1 142
Proximity Label-MS Homo sapiens
180 RNF2  
Affinity Capture-MS Homo sapiens
181 SF3B3 23450
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
182 FOXQ1  
Affinity Capture-MS Homo sapiens
183 ARGLU1  
Affinity Capture-MS Homo sapiens
184 PEX3 8504
Proximity Label-MS Homo sapiens
185 RIPK4  
Affinity Capture-MS Homo sapiens
186 IRF3 3661
Affinity Capture-MS Homo sapiens
187 RAE1 8480
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
188 HAUS3  
Affinity Capture-MS Homo sapiens
189 CCDC8  
Affinity Capture-MS Homo sapiens
190 MTA2 9219
Co-fractionation Homo sapiens
191 GTF3C4 9329
Affinity Capture-MS Homo sapiens
192 FTL 2512
Affinity Capture-MS Homo sapiens
193 STYXL1  
Affinity Capture-MS Homo sapiens
194 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
195 MKRN1 23608
Affinity Capture-MS Homo sapiens
196 SIRT6  
Affinity Capture-MS Homo sapiens
197 KIF14 9928
Affinity Capture-MS Homo sapiens
198 PEX1 5189
Affinity Capture-MS Homo sapiens
199 SRRM1 10250
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
200 CDK8 1024
Co-purification Homo sapiens
201 MBD3 53615
Co-fractionation Homo sapiens
202 SSU72 29101
Affinity Capture-Western Homo sapiens
203 FOXJ2  
Affinity Capture-MS Homo sapiens
204 FOXB1  
Affinity Capture-MS Homo sapiens
205 CHTF18 63922
Affinity Capture-Western Homo sapiens
206 RPA1 6117
Affinity Capture-MS Homo sapiens
207 MEN1 4221
Affinity Capture-MS Homo sapiens
208 SYCP3  
Affinity Capture-Western Homo sapiens
209 NGEF  
Affinity Capture-MS Homo sapiens
210 ARMCX3 51566
Co-fractionation Homo sapiens
211 PRPF19 27339
Affinity Capture-MS Homo sapiens
212 NEMF 9147
Co-fractionation Homo sapiens
213 MLH1 4292
Affinity Capture-MS Homo sapiens
214 CWF19L2  
Affinity Capture-MS Homo sapiens
215 MAGEA9  
Affinity Capture-MS Homo sapiens
216 POLR1A 25885
Co-fractionation Homo sapiens
217 ESR1  
Reconstituted Complex Homo sapiens
218 STAG1  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
219 KDM1B  
Affinity Capture-Western Homo sapiens
220 Ksr1  
Affinity Capture-MS Mus musculus
221 OSBPL3 26031
Affinity Capture-MS Homo sapiens
222 RSRC1  
Affinity Capture-MS Homo sapiens
223 NCL 4691
Affinity Capture-MS Homo sapiens
224 BECN1 8678
Affinity Capture-MS Homo sapiens
225 ARHGAP36  
Affinity Capture-MS Homo sapiens
226 CDK4 1019
Affinity Capture-MS Homo sapiens
227 RAD21 5885
Co-localization Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 AIRE  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
229 PINK1  
Affinity Capture-MS Homo sapiens
230 AKR7A2 8574
Affinity Capture-MS Homo sapiens
231 EP300 2033
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
232 ELF2  
Proximity Label-MS Homo sapiens
233 CUL7 9820
Affinity Capture-MS Homo sapiens
234 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
235 C9orf72  
Affinity Capture-MS Homo sapiens
236 HAUS2  
Affinity Capture-MS Homo sapiens
237 NEK9 91754
Affinity Capture-MS Homo sapiens
238 MYC  
Affinity Capture-MS Homo sapiens
239 NDC80 10403
Co-fractionation Homo sapiens
240 IVNS1ABP  
Affinity Capture-MS Homo sapiens
241 ARHGEF10L 55160
Affinity Capture-MS Homo sapiens
242 Nr1i3  
Affinity Capture-MS Mus musculus
Reconstituted Complex Mus musculus
243 SP7  
Affinity Capture-MS Homo sapiens
244 TRIM43  
Affinity Capture-MS Homo sapiens
245 NOTCH1 4851
Affinity Capture-MS Homo sapiens
246 CUL4A 8451
Affinity Capture-MS Homo sapiens
247 STAG3 10734
Affinity Capture-Western Homo sapiens
248 CDC5L 988
Affinity Capture-MS Homo sapiens
249 DERL1 79139
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here