Gene description for CHTF18
Gene name CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
Gene symbol CHTF18
Other names/aliases C16orf41
C321D2.2
C321D2.3
C321D2.4
CHL12
Ctf18
RUVBL
Species Homo sapiens
 Database cross references - CHTF18
ExoCarta ExoCarta_63922
Entrez Gene 63922
HGNC 18435
MIM 613201
UniProt Q8WVB6  
 CHTF18 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CHTF18
Molecular Function
    ATP binding GO:0005524 IEA
    DNA binding GO:0003677 IEA
Biological Process
    DNA replication GO:0006260 IEA
    spermatogenesis GO:0007283 IEA
    male meiosis GO:0007140 IEA
    negative regulation of chromosome segregation GO:0051985 IEA
    reciprocal meiotic recombination GO:0007131 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    membrane GO:0016020 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified CHTF18 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CHTF18
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSPA4 3308
Affinity Capture-MS Homo sapiens
2 RFC3 5983
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
3 PCNA 5111
Invitro Homo sapiens
Invivo Homo sapiens
Invitro Homo sapiens
4 RFC2 5982
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
5 DCC1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
6 SMC1A 8243
Affinity Capture-Western Homo sapiens
7 RFC5 5985
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
8 RAD21 5885
Affinity Capture-Western Homo sapiens
9 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
10 DERPC  
Affinity Capture-Western Homo sapiens
11 RFC4 5984
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which CHTF18 is involved
No pathways found





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