Experiment description of studies that identified JAKMIP1 in sEVs

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for JAKMIP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 YWHAH 7533 Affinity Capture-MS Homo sapiens 2 DDX6 1656 Two-hybrid Homo sapiens 3 MCRS1   Two-hybrid Homo sapiens 4 ENKD1   Two-hybrid Homo sapiens 5 CLASP2 23122 Affinity Capture-MS Homo sapiens 6 YWHAB 7529 Affinity Capture-MS Homo sapiens 7 SCNM1   Two-hybrid Homo sapiens 8 YWHAE 7531 Affinity Capture-MS Homo sapiens 9 ZNHIT2 741 Two-hybrid Homo sapiens 10 CHTF18 63922 Affinity Capture-MS Homo sapiens 11 TSGA10IP   Two-hybrid Homo sapiens 12 YWHAZ 7534 Affinity Capture-MS Homo sapiens 13 TUBB4B 10383 Affinity Capture-MS Homo sapiens 14 IL16   Two-hybrid Homo sapiens 15 DCLRE1C   Affinity Capture-MS Homo sapiens 16 MAPRE1 22919 Affinity Capture-MS Homo sapiens 17 BLK 640 Two-hybrid Homo sapiens 18 CHRM3 1131 Two-hybrid Homo sapiens 19 CLASP1 23332 Affinity Capture-MS Homo sapiens 20 MARK2 2011 Affinity Capture-MS Homo sapiens 21 CBX8 57332 Two-hybrid Homo sapiens 22 C18orf25 147339 Two-hybrid Homo sapiens 23 GABBR1   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 24 DCTN1 1639 Proximity Label-MS Homo sapiens 25 YES1 7525 Two-hybrid Homo sapiens 26 CLIP4   Affinity Capture-MS Homo sapiens 27 YWHAG 7532 Affinity Capture-MS Homo sapiens 28 MRPL11 65003 Two-hybrid Homo sapiens 29 PRMT1 3276 Affinity Capture-MS Homo sapiens 30 RANGAP1 5905 Cross-Linking-MS (XL-MS) Homo sapiens View the network

Pathways in which JAKMIP1 is involved

No pathways found