Experiment description of studies that identified C18orf25 in exosomes

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for C18orf25

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MCRS1   Two-hybrid Homo sapiens 2 MTHFR 4524 Affinity Capture-MS Homo sapiens 3 MED17   Affinity Capture-MS Homo sapiens 4 CSNK2A2 1459 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 SRPK2 6733 Biochemical Activity Homo sapiens 6 VSX2 338917 Affinity Capture-MS Homo sapiens 7 CSNK2A1 1457 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 TMA16   Affinity Capture-MS Homo sapiens 9 JUNB   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 JAKMIP1 152789 Two-hybrid Homo sapiens 11 UBE2O 63893 Affinity Capture-MS Homo sapiens 12 PTPN4   Affinity Capture-MS Homo sapiens 13 ZNF460   Affinity Capture-MS Homo sapiens 14 SIRT1   Affinity Capture-MS Homo sapiens 15 SYT2   Affinity Capture-MS Homo sapiens 16 SRP14 6727 Affinity Capture-MS Homo sapiens 17 TCEANC2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 INO80E   Affinity Capture-MS Homo sapiens 19 TCEB3B   Affinity Capture-MS Homo sapiens 20 ABT1 29777 Affinity Capture-MS Homo sapiens 21 GPN1   Co-fractionation Homo sapiens 22 CSNK2B 1460 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 PES1 23481 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 ZNF550   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 HLX   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 PNKP 11284 Affinity Capture-MS Homo sapiens 27 SHMT1 6470 Co-fractionation Homo sapiens 28 GOLGA8G   Affinity Capture-MS Homo sapiens 29 ATF2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 CBX3 11335 Proximity Label-MS Homo sapiens 31 UBE2I 7329 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 32 ZXDB   Affinity Capture-MS Homo sapiens 33 ZFP41   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 BBS1 582 Affinity Capture-MS Homo sapiens 35 RPL31 6160 Proximity Label-MS Homo sapiens 36 CDKN3 1033 Affinity Capture-MS Homo sapiens 37 SIX5   Affinity Capture-MS Homo sapiens 38 SUMO2 6613 Two-hybrid Homo sapiens 39 CREB3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 FEZF1   Affinity Capture-MS Homo sapiens 41 GSG2   Affinity Capture-MS Homo sapiens 42 SP110   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 HIST1H2BK 85236 Cross-Linking-MS (XL-MS) Homo sapiens 44 PPM1G 5496 Affinity Capture-MS Homo sapiens 45 CEBPA   Proximity Label-MS Homo sapiens 46 SRPK1 6732 Biochemical Activity Homo sapiens 47 CT45A5   Affinity Capture-MS Homo sapiens 48 TAF7L   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 CD3EAP   Proximity Label-MS Homo sapiens 50 KIF1B 23095 Co-fractionation Homo sapiens 51 FGF8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 CTSK 1513 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 TAX1BP1 8887 Two-hybrid Homo sapiens 54 XPO1 7514 Affinity Capture-MS Homo sapiens 55 FGF12   Affinity Capture-MS Homo sapiens 56 BATF3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 SEC24A 10802 Co-fractionation Homo sapiens 58 KCNE3   Affinity Capture-MS Homo sapiens 59 PIP4K2A 5305 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 60 DGKZ   Affinity Capture-MS Homo sapiens 61 ZNF692   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 62 TFPI2 7980 Affinity Capture-MS Homo sapiens 63 HSPA1A 3303 Affinity Capture-MS Homo sapiens 64 SORBS3 10174 Affinity Capture-MS Homo sapiens 65 SUMO1P1   Two-hybrid Homo sapiens 66 CCDC140   Affinity Capture-MS Homo sapiens 67 HIST1H2BC 8347 Cross-Linking-MS (XL-MS) Homo sapiens 68 ZNF263   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 SUMO1 7341 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 70 LLGL2 3993 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 71 ARRB2 409 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 FGF11   Affinity Capture-MS Homo sapiens 73 H2BFWT   Affinity Capture-MS Homo sapiens 74 ZRANB2 9406 Co-fractionation Homo sapiens 75 PLCD3 113026 Affinity Capture-MS Homo sapiens 76 KPNA6 23633 Affinity Capture-MS Homo sapiens 77 PLEKHJ1   Affinity Capture-MS Homo sapiens 78 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 79 DDIT4L   Two-hybrid Homo sapiens 80 RPS5 6193 Co-fractionation Homo sapiens 81 DHX40   Proximity Label-MS Homo sapiens 82 HOXC8   Affinity Capture-MS Homo sapiens 83 EEF1D 1936 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 84 SLC25A51   Proximity Label-MS Homo sapiens 85 ALX3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 86 BOP1 23246 Co-fractionation Homo sapiens 87 CDK11A 728642 Affinity Capture-MS Homo sapiens 88 UBA52 7311 Affinity Capture-MS Homo sapiens View the network

Pathways in which C18orf25 is involved

No pathways found