Gene description for VSX2
Gene name visual system homeobox 2
Gene symbol VSX2
Other names/aliases CHX10
HOX10
MCOP2
MCOPCB3
RET1
Species Homo sapiens
 Database cross references - VSX2
ExoCarta ExoCarta_338917
Vesiclepedia VP_338917
Entrez Gene 338917
HGNC 1975
MIM 142993
UniProt P58304  
 VSX2 identified in exosomes derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for VSX2
Molecular Function
    sequence-specific DNA binding GO:0043565 IEA
Biological Process
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA
    transcription, DNA-templated GO:0006351 IEA
    visual perception GO:0007601 IEA
    negative regulation of cell proliferation GO:0008285 IEA
    cell fate commitment GO:0045165 IEA
    response to stimulus GO:0050896 IEA
    retinal bipolar neuron differentiation GO:0060040 IEA
    positive regulation of cell proliferation GO:0008284 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified VSX2 in exosomes
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for VSX2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PAX6  
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which VSX2 is involved
No pathways found





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