Experiment description of studies that identified CDKN3 in exosomes

1 Experiment ID 236 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Cytosolic markers ✘ EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for CDKN3

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CDK1 983 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 2 MS4A3   Invivo Homo sapiens Two-hybrid Homo sapiens 3 CDC25A   Invitro Homo sapiens 4 CDK2 1017 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Invitro Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 5 CDK3 1018 Two-hybrid Homo sapiens Invivo Homo sapiens 6 CEBPA   Invivo Homo sapiens 7 CDKN3 1033 Two-hybrid Homo sapiens Two-hybrid Homo sapiens View the network

Pathways in which CDKN3 is involved

No pathways found