Gene description for BLK
Gene name
BLK proto-oncogene, Src family tyrosine kinase
Gene symbol
BLK
Other names/aliases
MODY11
Species
Homo sapiens
Database cross references - BLK
ExoCarta
ExoCarta_640
Vesiclepedia
VP_640
Entrez Gene
640
HGNC
1057
MIM
191305
UniProt
P51451
BLK identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for BLK
Experiment description of studies that identified BLK in exosomes
1
Experiment ID
211
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
EV Enriched markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
MISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
EV Enriched markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for BLK
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PLCG2
5336
Reconstituted Complex
Homo sapiens
2
CBL
867
Invitro
Homo sapiens
3
BCL2L1
598
Reconstituted Complex
Homo sapiens
4
CTR9
9646
Invitro
Homo sapiens
5
UBE3A
7337
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
6
BCAS2
10286
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
7
BCL2
Reconstituted Complex
Homo sapiens
8
CD79A
Affinity Capture-Western
Homo sapiens
9
CD79B
974
Affinity Capture-Western
Homo sapiens
View the network
image/svg+xml
Pathways in which BLK is involved