Experiment description of studies that identified FXR2 in exosomes

1 Experiment ID 207 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|HSP70 EV Cytosolic markers ✔ FLOT1 EV Membrane markers ✔ VDAC EV Negative markers ✔ NTA EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DKO-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

2 Experiment ID 208 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|HSP70 EV Cytosolic markers ✔ FLOT1 EV Membrane markers ✔ VDAC EV Negative markers ✔ NTA EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name Dks-8 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 209 ISEV standards ✘ EV Biophysical techniques ✔ TSG101|HSP70 EV Cytosolic markers ✔ FLOT1 EV Membrane markers ✔ VDAC EV Negative markers ✔ NTA EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DLD-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for FXR2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CBS 875 Two-hybrid Homo sapiens 2 MCRS1   Two-hybrid Homo sapiens 3 RALYL 138046 Two-hybrid Homo sapiens 4 HNRNPC 3183 Two-hybrid Homo sapiens 5 C10orf62   Two-hybrid Homo sapiens 6 RABAC1   Two-hybrid Homo sapiens 7 NDP52   Two-hybrid Homo sapiens 8 TRIM29   Two-hybrid Homo sapiens 9 SNAP23 8773 Two-hybrid Homo sapiens 10 KCNRG   Two-hybrid Homo sapiens 11 RBPMS   Two-hybrid Homo sapiens 12 SSSCA1   Two-hybrid Homo sapiens 13 PSME3 10197 Two-hybrid Homo sapiens 14 RBMX 27316 Two-hybrid Homo sapiens 15 FXR1 8087 Invivo Homo sapiens Invitro Homo sapiens Co-purification Homo sapiens 16 CRSP9   Affinity Capture-MS Homo sapiens 17 TSC22D4   Two-hybrid Homo sapiens 18 RTN3 10313 Two-hybrid Homo sapiens 19 AP1M1 8907 Two-hybrid Homo sapiens 20 KCTD4   Two-hybrid Homo sapiens 21 KIAA1217 56243 Two-hybrid Homo sapiens 22 TRAF2   Two-hybrid Homo sapiens 23 ZBTB8   Two-hybrid Homo sapiens 24 ARL6IP1 23204 Two-hybrid Homo sapiens 25 FTH1 2495 Two-hybrid Homo sapiens 26 KRT20 54474 Two-hybrid Homo sapiens 27 CYFIP2 26999 Affinity Capture-MS Homo sapiens 28 CCDC33 80125 Two-hybrid Homo sapiens 29 NONO 4841 Two-hybrid Homo sapiens 30 NCK2 8440 Two-hybrid Homo sapiens 31 THAP1   Two-hybrid Homo sapiens 32 AP2M1 1173 Two-hybrid Homo sapiens 33 NT5C2 22978 Two-hybrid Homo sapiens 34 DIPA   Two-hybrid Homo sapiens 35 DPPA2   Two-hybrid Homo sapiens 36 TRIM37   Two-hybrid Homo sapiens 37 MBIP   Two-hybrid Homo sapiens 38 LCMT1 51451 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 39 EFCBP2   Two-hybrid Homo sapiens 40 FXR2 9513 Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 41 AMOTL2   Two-hybrid Homo sapiens 42 FMR1   Invivo Homo sapiens Invivo Homo sapiens Invitro Homo sapiens Invitro Homo sapiens Co-purification Homo sapiens Reconstituted Complex Homo sapiens 43 FBP1 2203 Two-hybrid Homo sapiens 44 FLJ11730   Two-hybrid Homo sapiens 45 PCBD1 5092 Two-hybrid Homo sapiens 46 LDOC1   Two-hybrid Homo sapiens 47 GKAP1   Two-hybrid Homo sapiens 48 MGC2749   Two-hybrid Homo sapiens 49 CYFIP1 23191 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 50 RPIA 22934 Two-hybrid Homo sapiens 51 ZNF451 26036 Two-hybrid Homo sapiens 52 RTN4 57142 Two-hybrid Homo sapiens 53 PAICS 10606 Two-hybrid Homo sapiens 54 RBBP8   Two-hybrid Homo sapiens 55 TNNT1   Two-hybrid Homo sapiens View the network

Pathways in which FXR2 is involved

No pathways found