Gene description for AAMP
Gene name angio-associated, migratory cell protein
Gene symbol AAMP
Other names/aliases -
Species Homo sapiens
 Database cross references - AAMP
ExoCarta ExoCarta_14
Entrez Gene 14
HGNC 18
MIM 603488
UniProt Q13685  
 AAMP identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for AAMP
Molecular Function
    heparin binding GO:0008201 TAS
Biological Process
    cell differentiation GO:0030154 IEA
    angiogenesis GO:0001525 NAS
    smooth muscle cell migration GO:0014909 IEP
    positive regulation of endothelial cell migration GO:0010595 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    plasma membrane GO:0005886 IEA
    cell surface GO:0009986 IDA
 Experiment description of studies that identified AAMP in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for AAMP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AAMP is involved
No pathways found





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