Gene description for CD6
Gene name CD6 molecule
Gene symbol CD6
Other names/aliases TP120
Species Homo sapiens
 Database cross references - CD6
ExoCarta ExoCarta_923
Entrez Gene 923
HGNC 1691
MIM 186720
UniProt P30203  
 CD6 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CD6
Molecular Function
    scavenger receptor activity GO:0005044 IEA
    protein binding GO:0005515 IPI
Biological Process
    receptor-mediated endocytosis GO:0006898 IEA
    cell adhesion GO:0007155 IEA
Subcellular Localization
    integral component of plasma membrane GO:0005887 TAS
 Experiment description of studies that identified CD6 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MYC  
Affinity Capture-Western Homo sapiens
2 ALCAM 214
Reconstituted Complex Homo sapiens
3 CD5 921
FRET Homo sapiens
View the network image/svg+xml
 Pathways in which CD6 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here