Gene description for KIF18B
Gene name kinesin family member 18B
Gene symbol KIF18B
Other names/aliases -
Species Homo sapiens
 Database cross references - KIF18B
ExoCarta ExoCarta_146909
Vesiclepedia VP_146909
Entrez Gene 146909
HGNC 27102
MIM 614570
UniProt Q86Y91  
 KIF18B identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for KIF18B
Molecular Function
    cytoskeletal motor activity GO:0003774 IDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    microtubule binding GO:0008017 IBA
    plus-end-directed microtubule motor activity GO:0008574 IBA
    ATP hydrolysis activity GO:0016887 IBA
    kinesin binding GO:0019894 IPI
Biological Process
    mitotic sister chromatid segregation GO:0000070 IBA
    mitotic cell cycle GO:0000278 IDA
    microtubule-based movement GO:0007018 IBA
    microtubule depolymerization GO:0007019 IBA
    microtubule depolymerization GO:0007019 IDA
    cell division GO:0051301 IEA
    regulation of cell division GO:0051302 IDA
Subcellular Localization
    astral microtubule GO:0000235 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    kinesin complex GO:0005871 IBA
    nuclear body GO:0016604 IDA
    microtubule plus-end GO:0035371 IDA
    mitotic spindle astral microtubule GO:0061673 IBA
    mitotic spindle midzone GO:1990023 IBA
    microtubule end GO:1990752 IDA
 Experiment description of studies that identified KIF18B in exosomes
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for KIF18B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBXN6 80700
Affinity Capture-MS Homo sapiens
2 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
3 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
4 PPP1CB 5500
Affinity Capture-MS Homo sapiens
5 ASF1A 25842
Proximity Label-MS Homo sapiens
6 PARP1 142
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
7 CENPA  
Proximity Label-MS Homo sapiens
8 Cdc23  
Affinity Capture-MS Mus musculus
9 S100A6 6277
Affinity Capture-MS Homo sapiens
10 P4HA2 8974
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 NUP62 23636
Affinity Capture-MS Homo sapiens
12 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
13 Pparg 19016
Affinity Capture-MS Mus musculus
14 TXLNB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 CD6 923
Affinity Capture-MS Homo sapiens
16 CUL3 8452
Affinity Capture-MS Homo sapiens
17 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
18 PLOD1 5351
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 PNMA2  
Affinity Capture-MS Homo sapiens
20 LTN1 26046
Affinity Capture-MS Homo sapiens
21 DDX58 23586
Affinity Capture-RNA Homo sapiens
22 MKI67  
Affinity Capture-MS Homo sapiens
23 KPNA2 3838
Affinity Capture-MS Homo sapiens
24 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
25 MAPRE1 22919
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 NXF1 10482
Affinity Capture-RNA Homo sapiens
27 APEX1 328
Proximity Label-MS Homo sapiens
28 AHCYL2 23382
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 MAPRE3  
Affinity Capture-MS Homo sapiens
30 NUP50 10762
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 MRFAP1L1  
Affinity Capture-MS Homo sapiens
32 IMP3 55272
Affinity Capture-MS Homo sapiens
33 S100A4 6275
Affinity Capture-MS Homo sapiens
34 MOV10 4343
Affinity Capture-RNA Homo sapiens
35 KIF1BP 26128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 RPA3 6119
Proximity Label-MS Homo sapiens
37 SPRTN  
Affinity Capture-MS Homo sapiens
38 SUMO2 6613
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
39 FZR1  
Biochemical Activity Homo sapiens
40 NELL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 PTGES3 10728
Affinity Capture-MS Homo sapiens
42 Mapre1 13589
Affinity Capture-MS Mus musculus
43 ANAPC4 29945
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
44 FBLN5 10516
Affinity Capture-MS Homo sapiens
45 BRPF3  
Affinity Capture-MS Homo sapiens
46 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 Ppp1cb 19046
Affinity Capture-MS Mus musculus
48 CCT8L2  
Affinity Capture-MS Homo sapiens
49 HIST1H3A 8350
Proximity Label-MS Homo sapiens
50 KPNB1 3837
Affinity Capture-MS Homo sapiens
51 KIF2B 84643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 S100A2 6273
Affinity Capture-MS Homo sapiens
53 RUFY3  
Affinity Capture-MS Homo sapiens
54 KIF2C 11004
Affinity Capture-MS Homo sapiens
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