Gene description for IMP3
Gene name IMP3, U3 small nucleolar ribonucleoprotein
Gene symbol IMP3
Other names/aliases BRMS2
C15orf12
MRPS4
Species Homo sapiens
 Database cross references - IMP3
ExoCarta ExoCarta_55272
Entrez Gene 55272
HGNC 14497
MIM 612980
UniProt Q9NV31  
 IMP3 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for IMP3
Molecular Function
    protein binding GO:0005515 IPI
    structural constituent of ribosome GO:0003735 IBA
    rRNA binding GO:0019843 IBA
    snoRNA binding GO:0030515 IBA
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    rRNA processing GO:0006364 IBA
    positive regulation of translational fidelity GO:0045903 IBA
Subcellular Localization
    nucleus GO:0005634 IDA
    small ribosomal subunit GO:0015935 IBA
    small-subunit processome GO:0032040 IBA
    nucleolus GO:0005730 IDA
    Mpp10 complex GO:0034457 IBA
 Experiment description of studies that identified IMP3 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IMP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LPXN  
Two-hybrid Homo sapiens
2 MPHOSPH10  
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which IMP3 is involved
No pathways found





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