Gene description for KIF1A
Gene name kinesin family member 1A
Gene symbol KIF1A
Other names/aliases ATSV
Species Homo sapiens
 Database cross references - KIF1A
ExoCarta ExoCarta_547
Entrez Gene 547
HGNC 888
MIM 601255
UniProt Q12756  
 KIF1A identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for KIF1A
Molecular Function
    motor activity GO:0003774 TAS
    ATP binding GO:0005524 IEA
    ATP-dependent microtubule motor activity, plus-end-directed GO:0008574 IBA
    microtubule binding GO:0008017 IEA
Biological Process
    metabolic process GO:0008152 TAS
    vesicle-mediated transport GO:0016192 IBA
    anterograde axon cargo transport GO:0008089 TAS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    neuron projection GO:0043005 IEA
    microtubule GO:0005874 IEA
    neuronal cell body GO:0043025 IEA
    kinesin complex GO:0005871 IBA
 Experiment description of studies that identified KIF1A in exosomes
Experiment ID 237
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for KIF1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GIT1 28964
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which KIF1A is involved
No pathways found

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