Gene description for RBPMS
Gene name RNA binding protein with multiple splicing
Gene symbol RBPMS
Other names/aliases HERMES
Species Homo sapiens
 Database cross references - RBPMS
ExoCarta ExoCarta_11030
Vesiclepedia VP_11030
Entrez Gene 11030
HGNC 19097
MIM 601558
UniProt Q93062  
 RBPMS identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for RBPMS
Molecular Function
    transcription coactivator activity GO:0003713 IDA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IDA
    mRNA binding GO:0003729 IBA
    mRNA 3'-UTR binding GO:0003730 IDA
    protein binding GO:0005515 IPI
    protein homodimerization activity GO:0042803 IPI
    molecular adaptor activity GO:0060090 ISS
    pre-mRNA intronic binding GO:0097157 IDA
    mRNA CDS binding GO:1990715 IDA
Biological Process
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 ISS
    RNA processing GO:0006396 TAS
    response to oxidative stress GO:0006979 IMP
    positive regulation of DNA-templated transcription GO:0045893 IEA
    SMAD protein signal transduction GO:0060395 IDA
    protein-containing complex assembly GO:0065003 ISS
Subcellular Localization
    P-body GO:0000932 IEA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    cytoplasmic stress granule GO:0010494 IDA
 Experiment description of studies that identified RBPMS in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for RBPMS
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CRBN  
Two-hybrid Homo sapiens
2 MVP 9961
Two-hybrid Homo sapiens
3 GRAP2 9402
Two-hybrid Homo sapiens
4 TUSC2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
5 PRKAA1 5562
Two-hybrid Homo sapiens
6 EXOSC7 23016
Two-hybrid Homo sapiens
7 ZNF488  
Two-hybrid Homo sapiens
8 POLDIP3 84271
Two-hybrid Homo sapiens
9 SNRPG 6637
Two-hybrid Homo sapiens
10 PER1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
11 PITX2  
Two-hybrid Homo sapiens
12 RBPMS 11030
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
13 Ran 19384
Two-hybrid Mus musculus
14 TEKT5  
Two-hybrid Homo sapiens
15 KRTAP19-1  
Two-hybrid Homo sapiens
16 RBM22 55696
Two-hybrid Homo sapiens
17 GSTZ1 2954
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 BUB1  
Affinity Capture-MS Homo sapiens
19 Ckap5 75786
Affinity Capture-MS Mus musculus
20 CRYBA1  
Two-hybrid Homo sapiens
21 YTHDF1 54915
Two-hybrid Homo sapiens
22 PKP2 5318
Two-hybrid Homo sapiens
23 ATXN1 6310
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
24 AES 166
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
25 ATP6V0E2  
Two-hybrid Homo sapiens
26 POGZ 23126
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
27 C19orf54  
Two-hybrid Homo sapiens
28 HOXA9  
Two-hybrid Homo sapiens
29 QKI 9444
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
30 FASTK  
Two-hybrid Homo sapiens
31 PLSCR4  
Two-hybrid Homo sapiens
32 DYNC1I1  
Two-hybrid Homo sapiens
33 GLYCTK  
Two-hybrid Homo sapiens
34 MRPL10 124995
Two-hybrid Homo sapiens
35 SLIRP 81892
Two-hybrid Homo sapiens
36 WDYHV1  
Two-hybrid Homo sapiens
37 EYA2  
Two-hybrid Homo sapiens
38 VHL  
Reconstituted Complex Homo sapiens
39 BANP  
Two-hybrid Homo sapiens
40 ZNF34  
Two-hybrid Homo sapiens
41 RHOXF2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
42 C1orf94  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
43 ATN1  
Two-hybrid Homo sapiens
44 MRPL44  
Two-hybrid Homo sapiens
45 LINC00588  
Two-hybrid Homo sapiens
46 HNRNPLL 92906
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
47 KRTAP19-5  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
48 SPG7  
Two-hybrid Homo sapiens
49 APEX1 328
Affinity Capture-RNA Homo sapiens
50 TSPYL6  
Two-hybrid Homo sapiens
51 CCNK  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
52 FAM103A1  
Two-hybrid Homo sapiens
53 RDX 5962
Two-hybrid Homo sapiens
54 C20orf85  
Two-hybrid Homo sapiens
55 C11orf87  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
56 GSE1 23199
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
57 ZNF385C  
Two-hybrid Homo sapiens
58 INIP  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
59 PLAC8  
Two-hybrid Homo sapiens
60 TBX6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
61 DDX28  
Two-hybrid Homo sapiens
62 COL8A1 1295
Two-hybrid Homo sapiens
63 CPSF7 79869
Two-hybrid Homo sapiens
64 KRTAP11-1  
Two-hybrid Homo sapiens
65 PRR20A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
66 OLFM4 10562
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 IP6K2  
Two-hybrid Homo sapiens
68 SIRPB1 10326
Two-hybrid Homo sapiens
69 PGLS 25796
Two-hybrid Homo sapiens
70 EWSR1 2130
Two-hybrid Homo sapiens
71 DCTN5 84516
Two-hybrid Homo sapiens
72 LINC00482  
Two-hybrid Homo sapiens
73 LRRC75A-AS1  
Two-hybrid Homo sapiens
74 ANAPC11  
Two-hybrid Homo sapiens
75 SNRPC 6631
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
76 IGF2 3481
Two-hybrid Homo sapiens
77 KRTAP13-3  
Two-hybrid Homo sapiens
78 ESRP1 54845
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 FRG1 2483
Two-hybrid Homo sapiens
80 Mbp 17196
Two-hybrid Mus musculus
81 ARID5A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
82 SERF2 10169
Two-hybrid Homo sapiens
83 PHF1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
84 PDLIM4 8572
Two-hybrid Homo sapiens
85 ROR2 4920
Two-hybrid Homo sapiens
86 FBF1  
Two-hybrid Homo sapiens
87 FEM1A  
Affinity Capture-MS Homo sapiens
88 YPEL3  
Two-hybrid Homo sapiens
89 ARHGAP9 64333
Two-hybrid Homo sapiens
90 FOXP3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
91 LMO4  
Two-hybrid Homo sapiens
92 DVL2 1856
Two-hybrid Homo sapiens
93 LARP4B 23185
Two-hybrid Homo sapiens
94 DMRTB1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
95 RTP5  
Two-hybrid Homo sapiens
96 ATXN2 6311
Affinity Capture-MS Homo sapiens
97 SLC25A48  
Two-hybrid Homo sapiens
98 NEDD9 4739
Two-hybrid Homo sapiens
99 PRPF6 24148
Two-hybrid Homo sapiens
100 RDH12 145226
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
101 WBP4  
Two-hybrid Homo sapiens
102 VEZF1  
Two-hybrid Homo sapiens
103 TSGA10IP  
Two-hybrid Homo sapiens
104 FOXA1  
Affinity Capture-MS Homo sapiens
105 DPYSL4 10570
Two-hybrid Homo sapiens
106 AMMECR1  
Two-hybrid Homo sapiens
107 CEP55 55165
Two-hybrid Homo sapiens
108 VHLL  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
109 CDC23 8697
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
110 LINC00908  
Two-hybrid Homo sapiens
111 SBF2 81846
Two-hybrid Homo sapiens
112 HCK 3055
Two-hybrid Homo sapiens
113 TINAGL1 64129
Two-hybrid Homo sapiens
114 GLIS2  
Two-hybrid Homo sapiens
115 ZMAT5  
Two-hybrid Homo sapiens
116 KRTAP12-1  
Two-hybrid Homo sapiens
117 TCEA2  
Two-hybrid Homo sapiens
118 RBM7  
Two-hybrid Homo sapiens
119 DOK3 79930
Two-hybrid Homo sapiens
120 KRTAP19-7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
121 NMNAT3 349565
Affinity Capture-MS Homo sapiens
122 ANKHD1 54882
Two-hybrid Homo sapiens
123 WDR90  
Two-hybrid Homo sapiens
124 KRTAP8-1  
Two-hybrid Homo sapiens
125 DAZAP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
126 CNNM3 26505
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
127 MGAT5B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
128 PRR35  
Two-hybrid Homo sapiens
129 POU6F2  
Two-hybrid Homo sapiens
130 CAMK2B 816
Two-hybrid Homo sapiens
131 MYH9 4627
Affinity Capture-MS Homo sapiens
132 HAO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 ZBTB32  
Two-hybrid Homo sapiens
134 Rbm47  
Two-hybrid Mus musculus
135 C20orf195  
Two-hybrid Homo sapiens
136 BCL6B  
Two-hybrid Homo sapiens
137 FOXC2  
Two-hybrid Homo sapiens
138 LONRF1  
Two-hybrid Homo sapiens
139 PATL1 219988
Two-hybrid Homo sapiens
140 SNRPN 6638
Two-hybrid Homo sapiens
141 PRMT2  
Affinity Capture-MS Homo sapiens
142 CSNK1G2-AS1  
Two-hybrid Homo sapiens
143 HEY2  
Two-hybrid Homo sapiens
144 SLAIN1 122060
Two-hybrid Homo sapiens
145 ZNF581  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
146 BOLL  
Two-hybrid Homo sapiens
147 APLN  
Two-hybrid Homo sapiens
148 MBNL2 10150
Two-hybrid Homo sapiens
149 NEU4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
150 BBS2 583
Two-hybrid Homo sapiens
151 TXNL4A 10907
Two-hybrid Homo sapiens
152 VENTX  
Two-hybrid Homo sapiens
153 DNTTIP2  
Two-hybrid Homo sapiens
154 FOXS1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
155 Pard6g  
Two-hybrid Mus musculus
156 CCDC120  
Two-hybrid Homo sapiens
157 KRTAP19-3  
Two-hybrid Homo sapiens
158 C22orf39  
Two-hybrid Homo sapiens
159 GPS2  
Two-hybrid Homo sapiens
160 CYBA 1535
Two-hybrid Homo sapiens
161 PCBP2 5094
Two-hybrid Homo sapiens
162 Nufip2  
Two-hybrid Mus musculus
163 PSG11  
Two-hybrid Homo sapiens
164 TRIP13 9319
Two-hybrid Homo sapiens
165 PICK1  
Affinity Capture-MS Homo sapiens
166 ATXN7L2  
Two-hybrid Homo sapiens
167 MAZ 4150
Two-hybrid Homo sapiens
168 ARHGEF39 84904
Two-hybrid Homo sapiens
169 C1orf111  
Two-hybrid Homo sapiens
170 C9orf24  
Two-hybrid Homo sapiens
171 NKX2-5  
Two-hybrid Homo sapiens
172 Rbm38  
Two-hybrid Mus musculus
173 KRTAP12-2  
Two-hybrid Homo sapiens
174 RBM46  
Two-hybrid Homo sapiens
175 PIP 5304
Affinity Capture-MS Homo sapiens
176 UBAP2 55833
Two-hybrid Homo sapiens
177 LY6G5B  
Affinity Capture-MS Homo sapiens
178 SNRPB 6628
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
179 TTLL10 254173
Two-hybrid Homo sapiens
180 KRTAP3-1  
Two-hybrid Homo sapiens
181 NAPRT 93100
Two-hybrid Homo sapiens
182 PRKAA2 5563
Two-hybrid Homo sapiens
183 CDC42EP1 11135
Two-hybrid Homo sapiens
184 RBPMS2  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
185 HYPK 25764
Affinity Capture-MS Homo sapiens
186 Rbm14  
Two-hybrid Mus musculus
187 GRAP  
Two-hybrid Homo sapiens
188 SF1 7536
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
189 PRR20D  
Two-hybrid Homo sapiens
190 BHLHE40  
Two-hybrid Homo sapiens
191 POM121  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
192 DTX2 113878
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
193 SH3RF2  
Two-hybrid Homo sapiens
194 RBFOX1 54715
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
195 LINC01547  
Two-hybrid Homo sapiens
196 HOXA1 3198
Two-hybrid Homo sapiens
197 KLHDC7B  
Two-hybrid Homo sapiens
198 SPATA8  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
199 KPNA2 3838
Two-hybrid Homo sapiens
200 OTX1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
201 TFG 10342
Two-hybrid Homo sapiens
202 ZC3H10  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
203 NXF1 10482
Two-hybrid Homo sapiens
204 Hoxa1  
Two-hybrid Mus musculus
Affinity Capture-Western Mus musculus
205 TMEM42  
Two-hybrid Homo sapiens
206 DCAF8 50717
Two-hybrid Homo sapiens
207 SMAP1 60682
Two-hybrid Homo sapiens
208 KRTAP12-4  
Two-hybrid Homo sapiens
209 RAD54L2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
210 R3HDM2  
Two-hybrid Homo sapiens
211 VGLL3  
Two-hybrid Homo sapiens
212 RBM42  
Two-hybrid Homo sapiens
213 RPP25  
Two-hybrid Homo sapiens
214 Nup107  
Affinity Capture-MS Mus musculus
215 FXR2 9513
Two-hybrid Homo sapiens
216 Rps19bp1  
Two-hybrid Mus musculus
217 MSI2 124540
Two-hybrid Homo sapiens
218 LOC142937  
Two-hybrid Homo sapiens
219 PRR20B  
Two-hybrid Homo sapiens
220 PAPD4 167153
Two-hybrid Homo sapiens
221 UNKL  
Two-hybrid Homo sapiens
222 KAT5  
Two-hybrid Homo sapiens
223 LINC01588  
Two-hybrid Homo sapiens
224 SNW1 22938
Two-hybrid Homo sapiens
225 TEX37  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
226 CCNG1  
Two-hybrid Homo sapiens
227 LRRC41 10489
Two-hybrid Homo sapiens
228 GCM2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
229 TMSB4X 7114
Two-hybrid Homo sapiens
230 PRKAB2 5565
Two-hybrid Homo sapiens
231 ZIC1  
Two-hybrid Homo sapiens
232 PRR20C  
Two-hybrid Homo sapiens
233 BAG4  
Two-hybrid Homo sapiens
234 Pcbp1 23983
Two-hybrid Mus musculus
235 SMUG1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
236 FAM120A 23196
Two-hybrid Homo sapiens
237 NIP7 51388
Two-hybrid Homo sapiens
238 CLPP 8192
Two-hybrid Homo sapiens
239 KCTD9  
Two-hybrid Homo sapiens
240