Gene description for RBM22
Gene name RNA binding motif protein 22
Gene symbol RBM22
Other names/aliases Cwc2
ZC3H16
fSAP47
Species Homo sapiens
 Database cross references - RBM22
ExoCarta ExoCarta_55696
Vesiclepedia VP_55696
Entrez Gene 55696
HGNC 25503
MIM 612430
UniProt Q9NW64  
 RBM22 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for RBM22
Molecular Function
    protein binding GO:0005515 IPI
    nucleotide binding GO:0000166 IEA
    nucleocytoplasmic transporter activity GO:0005487 IDA
    snRNA binding GO:0017069 IDA
    poly(A) RNA binding GO:0044822 IDA
    calcium-dependent protein binding GO:0048306 IPI
    pre-mRNA binding GO:0036002 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    mRNA cis splicing, via spliceosome GO:0045292 IDA
    positive regulation of RNA splicing GO:0033120 IDA
    mRNA splicing, via spliceosome GO:0000398 IC
    cellular response to drug GO:0035690 IDA
    positive regulation of intracellular protein transport GO:0090316 IDA
    protein import into nucleus, translocation GO:0000060 IDA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    catalytic step 2 spliceosome GO:0071013 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified RBM22 in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RBM22
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RBM22 is involved
No pathways found





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