Experiment description of studies that identified RALYL in sEVs

1 Experiment ID 191 MISEV standards ✘ Biophysical techniques ✔ Alix|CD81|CD9 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20124223     Organism Homo sapiens Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK." Journal name Mol Cell Proteomics Publication year 2010 Sample Squamous carcinoma cells Sample name Squamous carcinoma cell (A431) Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for RALYL

Protein Interactor ExoCarta ID Identification method PubMed Species 1 PCBP2 5094 Two-hybrid Homo sapiens 2 CCDC12   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 RALY 22913 Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 4 MCRS1   Two-hybrid Homo sapiens 5 ELAVL2 1993 Affinity Capture-MS Homo sapiens 6 TRAF7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 RALYL 138046 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 8 HNRNPC 3183 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 9 PRKRA 8575 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 EXOSC7 23016 Two-hybrid Homo sapiens 11 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 12 DGCR14   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 RBM22 55696 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 NXF1 10482 Two-hybrid Homo sapiens 15 KIF14 9928 Affinity Capture-MS Homo sapiens 16 KIF20A 10112 Affinity Capture-MS Homo sapiens 17 CCDC85B   Two-hybrid Homo sapiens 18 CDC40   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 PNN 5411 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 AEN   Two-hybrid Homo sapiens 21 CWF19L1 55280 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 YTHDC1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 ZC3H14   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 ISY1 57461 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 BYSL 705 Two-hybrid Homo sapiens 26 RBM41   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 27 VHL   Affinity Capture-MS Homo sapiens 28 CCDC9   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 AQR 9716 Affinity Capture-MS Homo sapiens 30 HNRNPCL1 343069 Two-hybrid Homo sapiens 31 XAB2 56949 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 THAP1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 33 PPIE 10450 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 SF3A1 10291 Affinity Capture-MS Homo sapiens 35 TIGD3   Two-hybrid Homo sapiens 36 KRR1 11103 Cross-Linking-MS (XL-MS) Homo sapiens 37 HNRNPCL2 440563 Two-hybrid Homo sapiens 38 C20orf27 54976 Two-hybrid Homo sapiens 39 CRNKL1 51340 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 ZNF408   Two-hybrid Homo sapiens 41 FXR2 9513 Two-hybrid Homo sapiens 42 RBM3 5935 Affinity Capture-MS Homo sapiens 43 KIF23 9493 Affinity Capture-MS Homo sapiens 44 DLST 1743 Affinity Capture-MS Homo sapiens 45 TSNAX 7257 Two-hybrid Homo sapiens 46 PSMF1 9491 Two-hybrid Homo sapiens 47 FBXW7   Synthetic Lethality Homo sapiens 48 PRC1 9055 Affinity Capture-MS Homo sapiens 49 CUL7 9820 Affinity Capture-MS Homo sapiens 50 Hnrnpk 15387 Two-hybrid Mus musculus 51 BRPF3   Affinity Capture-MS Homo sapiens 52 AEBP2   Two-hybrid Homo sapiens 53 EWSR1 2130 Two-hybrid Homo sapiens 54 Ube2i   Two-hybrid Mus musculus 55 CEP170P1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 56 SKA2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 LMO3   Two-hybrid Homo sapiens 58 LRRK2 120892 Two-hybrid Homo sapiens 59 Pcbp1 23983 Two-hybrid Mus musculus View the network

Pathways in which RALYL is involved

No pathways found