Gene description for RALYL
Gene name RALY RNA binding protein-like
Gene symbol RALYL
Other names/aliases HNRPCL3
Species Homo sapiens
 Database cross references - RALYL
ExoCarta ExoCarta_138046
Entrez Gene 138046
HGNC 27036
MIM 614648
UniProt Q86SE5  
 RALYL identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for RALYL
Molecular Function
    identical protein binding GO:0042802 IPI
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 IDA
    nucleotide binding GO:0000166 IEA
 Experiment description of studies that identified RALYL in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RALYL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DIPA  
Two-hybrid Homo sapiens
2 MCRS1  
Two-hybrid Homo sapiens
3 RALYL 138046
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
4 HNRNPC 3183
Two-hybrid Homo sapiens
5 AEBP2  
Two-hybrid Homo sapiens
6 FLJ11016  
Two-hybrid Homo sapiens
7 C20orf27 54976
Two-hybrid Homo sapiens
8 ZNF408  
Two-hybrid Homo sapiens
9 THAP1  
Two-hybrid Homo sapiens
10 FXR2 9513
Two-hybrid Homo sapiens
11 CEP170L  
Two-hybrid Homo sapiens
12 LMO3  
Two-hybrid Homo sapiens
13 EWSR1 2130
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RALYL is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here