Gene description for ELAVL2
Gene name ELAV like neuron-specific RNA binding protein 2
Gene symbol ELAVL2
Other names/aliases HEL-N1
HELN1
HUB
Species Homo sapiens
 Database cross references - ELAVL2
ExoCarta ExoCarta_1993
Vesiclepedia VP_1993
Entrez Gene 1993
HGNC 3313
MIM 601673
UniProt Q12926  
 ELAVL2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ELAVL2
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA 3'-UTR binding GO:0003730 TAS
    protein binding GO:0005515 IPI
Biological Process
    regulation of DNA-templated transcription GO:0006355 TAS
Subcellular Localization
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified ELAVL2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ELAVL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CCDC12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 RALY 22913
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 NUPL2 11097
Affinity Capture-MS Homo sapiens
4 RALYL 138046
Affinity Capture-MS Homo sapiens
5 HNRNPC 3183
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 ZC3H14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 ZBTB38 253461
Affinity Capture-MS Homo sapiens
8 DGCR14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 GCFC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 ZNF346  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 RBM22 55696
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 PABPC5 140886
Affinity Capture-MS Homo sapiens
13 TARDBP 23435
Affinity Capture-MS Homo sapiens
14 LIN28B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 LARP1B 55132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 GAPDHS 26330
Affinity Capture-MS Homo sapiens
17 RBMXL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 ZFR 51663
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 PUM2 23369
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 CAND1 55832
Affinity Capture-MS Homo sapiens
22 CCDC9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 AQR 9716
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 SYF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 SRSF8 10929
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 ZAR1L  
Affinity Capture-MS Homo sapiens
27 ILF2 3608
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 SAFB 6294
Affinity Capture-MS Homo sapiens
30 CAPZB 832
Affinity Capture-MS Homo sapiens
31 HNRNPAB 3182
Two-hybrid Homo sapiens
32 GSPT2 23708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 RNPS1 10921
Affinity Capture-MS Homo sapiens
34 PRR11  
Affinity Capture-MS Homo sapiens
35 CRNKL1 51340
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 Elavl1 15568
Affinity Capture-MS Mus musculus
37 RBM3 5935
Affinity Capture-MS Homo sapiens
38 KIF23 9493
Affinity Capture-MS Homo sapiens
39 PABPC4L 132430
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 ISY1 57461
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 SRSF10 10772
Affinity Capture-MS Homo sapiens
42 TRA2B 6434
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 SRRM2 23524
Affinity Capture-MS Homo sapiens
45 TFIP11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 C17orf85  
Affinity Capture-MS Homo sapiens
47 ZCCHC3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 STAU2 27067
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 PRKRA 8575
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 ESRP1 54845
Affinity Capture-MS Homo sapiens
51 MECP2 4204
Affinity Capture-MS Homo sapiens
52 MYCN  
Affinity Capture-MS Homo sapiens
53 PABPC4 8761
Affinity Capture-MS Homo sapiens
54 FAM120A 23196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 LARP4B 23185
Affinity Capture-MS Homo sapiens
56 ATXN2 6311
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 RBMX 27316
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 CLK2 1196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 CDKN2AIP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 QKI 9444
Affinity Capture-MS Homo sapiens
61 PPIE 10450
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 THAP3  
Affinity Capture-MS Homo sapiens
63 RBFOX2 23543
Two-hybrid Homo sapiens
64 PHAX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 YBX2 51087
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 ACIN1 22985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 SRSF6 6431
Affinity Capture-MS Homo sapiens
69 PURG  
Affinity Capture-MS Homo sapiens
70 SRRT 51593
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 PUM1 9698
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
73 PABPC1 26986
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 MKRN2 23609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 UBXN8  
Affinity Capture-MS Homo sapiens
76 SAFB2 9667
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 RSL1D1 26156
Affinity Capture-MS Homo sapiens
79 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
80 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 CBX6  
Affinity Capture-MS Homo sapiens
82 HECTD1 25831
Affinity Capture-MS Homo sapiens
83 CDX1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 GTPBP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 LARP1 23367
Affinity Capture-MS Homo sapiens
86 WDR46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 ZNF326 284695
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 PAIP2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 CWF19L1 55280
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 MAP7 9053
Affinity Capture-MS Homo sapiens
91 CLK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 NR3C1 2908
Proximity Label-MS Homo sapiens
93 RBM47 54502
Affinity Capture-MS Homo sapiens
94 PNN 5411
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 RTP3  
Affinity Capture-MS Homo sapiens
96 SRSF1 6426
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 CUL3 8452
Affinity Capture-MS Homo sapiens
98 XAB2 56949
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 ZC3H11A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 APOBEC3B 9582
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 TROVE2 6738
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 YTHDC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 CDK2 1017
Affinity Capture-MS Homo sapiens
104 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
105 HNRNPR 10236
Affinity Capture-MS Homo sapiens
106 DKC1 1736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 APOBEC3F 200316
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 PSPC1 55269
Affinity Capture-MS Homo sapiens
109 ZC3H18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 DAZL  
Affinity Capture-MS Homo sapiens
111 NCBP1 4686
Affinity Capture-MS Homo sapiens
112 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 MATR3 9782
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 SNW1 22938
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 DDRGK1 65992
Affinity Capture-MS Homo sapiens
116 BMI1  
Affinity Capture-MS Homo sapiens
117 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 ZC3H3  
Affinity Capture-MS Homo sapiens
119 CELF5  
Affinity Capture-MS Homo sapiens
120 ELAVL3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 RBMS2 5939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 H2AFX 3014
Affinity Capture-MS Homo sapiens
123 PAIP1 10605
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 YBX1 4904
Affinity Capture-MS Homo sapiens
125 ALG13 79868
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 RBM45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 ILF3 3609
Affinity Capture-MS Homo sapiens
128 IREB2 3658
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 CDC40  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 APOBEC3D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 POLR3H  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 PTBP3 9991
Affinity Capture-MS Homo sapiens
133 CWF19L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 CPEB1  
Affinity Capture-MS Homo sapiens
135 PRR3  
Affinity Capture-MS Homo sapiens
136 SUGP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 NR2E3  
Two-hybrid Homo sapiens
138 UFL1 23376
Affinity Capture-MS Homo sapiens
139 KRR1 11103
Affinity Capture-MS Homo sapiens
140 HOXC9  
Two-hybrid Homo sapiens
141 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 MOV10 4343
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 HNRNPL 3191
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 UPF1 5976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 RPS6 6194
Affinity Capture-MS Homo sapiens
146 GRSF1 2926
Proximity Label-MS Homo sapiens
147 LDLR 3949
Positive Genetic Homo sapiens
148 RPL23A 6147
Affinity Capture-MS Homo sapiens
149 CDC5L 988
Affinity Capture-MS Homo sapiens
150 MYC  
Affinity Capture-MS Homo sapiens
151 STRBP 55342
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 SRSF3 6428
Affinity Capture-MS Homo sapiens
153 IGF2BP2 10644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 CASC3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ELAVL2 is involved
No pathways found





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