Gene description for TRA2A
Gene name transformer 2 alpha homolog (Drosophila)
Gene symbol TRA2A
Other names/aliases AWMS1
Species Homo sapiens
 Database cross references - TRA2A
ExoCarta ExoCarta_29896
Entrez Gene 29896
HGNC 16645
MIM 602718
UniProt Q13595  
 TRA2A identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for TRA2A
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    nucleotide binding GO:0000166 IEA
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleolus GO:0005730 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified TRA2A in exosomes
Experiment ID 191
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TRA2A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SRSF10 10772
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TRA2A is involved
No pathways found

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