Gene description for MRPS5
Gene name mitochondrial ribosomal protein S5
Gene symbol MRPS5
Other names/aliases MRP-S5
S5mt
Species Homo sapiens
 Database cross references - MRPS5
ExoCarta ExoCarta_64969
Vesiclepedia VP_64969
Entrez Gene 64969
HGNC 14498
MIM 611972
UniProt P82675  
 MRPS5 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MRPS5
Molecular Function
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IBA
Biological Process
    translation GO:0006412 IBA
    mitochondrial translation GO:0032543 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial small ribosomal subunit GO:0005763 IBA
    mitochondrial small ribosomal subunit GO:0005763 IDA
    mitochondrial small ribosomal subunit GO:0005763 NAS
 Experiment description of studies that identified MRPS5 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MRPS5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 ZBTB38 253461
Affinity Capture-MS Homo sapiens
4 NUPL2 11097
Affinity Capture-MS Homo sapiens
5 MRPS27 23107
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 SLIRP 81892
Proximity Label-MS Homo sapiens
7 H1FNT  
Affinity Capture-MS Homo sapiens
8 SNX3 8724
Affinity Capture-MS Homo sapiens
9 RBMS3  
Affinity Capture-MS Homo sapiens
10 RPL36AL 6166
Affinity Capture-MS Homo sapiens
11 ZNF324B  
Affinity Capture-MS Homo sapiens
12 RBMS2 5939
Affinity Capture-MS Homo sapiens
13 LHX2  
Proximity Label-MS Homo sapiens
14 RPL13A 23521
Affinity Capture-MS Homo sapiens
15 RPL26 6154
Affinity Capture-MS Homo sapiens
16 TRUB2  
Proximity Label-MS Homo sapiens
17 KLF8  
Proximity Label-MS Homo sapiens
18 MTG2  
Proximity Label-MS Homo sapiens
19 NGRN  
Proximity Label-MS Homo sapiens
20 RPL10 6134
Affinity Capture-MS Homo sapiens
21 MRPL24  
Co-fractionation Homo sapiens
22 CAND1 55832
Affinity Capture-MS Homo sapiens
23 HNRNPR 10236
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 RPUSD4 84881
Proximity Label-MS Homo sapiens
25 DNAJC15  
Proximity Label-MS Homo sapiens
26 MTRF1  
Proximity Label-MS Homo sapiens
27 GFM2 84340
Proximity Label-MS Homo sapiens
28 CCDC90B  
Proximity Label-MS Homo sapiens
29 LRPPRC 10128
Proximity Label-MS Homo sapiens
30 RPL4 6124
Affinity Capture-MS Homo sapiens
31 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
32 ZBTB2 57621
Affinity Capture-MS Homo sapiens
33 MCU 90550
Proximity Label-MS Homo sapiens
34 SULF2 55959
Affinity Capture-MS Homo sapiens
35 CRYZ 1429
Proximity Label-MS Homo sapiens
36 TFAM 7019
Proximity Label-MS Homo sapiens
37 PMPCA 23203
Proximity Label-MS Homo sapiens
38 SDHB 6390
Co-fractionation Homo sapiens
39 ZNF485  
Affinity Capture-MS Homo sapiens
40 FBXW7  
Affinity Capture-MS Homo sapiens
41 HINT2 84681
Proximity Label-MS Homo sapiens
42 MRPS23 51649
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 MRPS24 64951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 ZNF460  
Affinity Capture-MS Homo sapiens
45 DDRGK1 65992
Affinity Capture-MS Homo sapiens
46 KLF15  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 RPS9 6203
Affinity Capture-MS Homo sapiens
48 MRPS26 64949
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 SURF1  
Proximity Label-MS Homo sapiens
50 ADARB1 104
Affinity Capture-MS Homo sapiens
51 EXD2  
Proximity Label-MS Homo sapiens
52 TULP3 7289
Affinity Capture-MS Homo sapiens
53 ERAL1  
Affinity Capture-MS Homo sapiens
54 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
55 KLF4  
Affinity Capture-MS Homo sapiens
56 E4F1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 ZNF689  
Affinity Capture-MS Homo sapiens
58 MRPS7 51081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 TLX3  
Proximity Label-MS Homo sapiens
60 PMPCB 9512
Proximity Label-MS Homo sapiens
61 RBM42  
Affinity Capture-MS Homo sapiens
62 FASTKD2  
Proximity Label-MS Homo sapiens
63 MTIF2 4528
Proximity Label-MS Homo sapiens
64 RPL19 6143
Affinity Capture-MS Homo sapiens
65 MTERF3  
Proximity Label-MS Homo sapiens
66 MZT1  
Affinity Capture-MS Homo sapiens
67 MDH2 4191
Proximity Label-MS Homo sapiens
68 SRSF6 6431
Affinity Capture-MS Homo sapiens
69 KLF16  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 ACTA2 59
Affinity Capture-MS Homo sapiens
71 MRPS25 64432
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 ZKSCAN8  
Affinity Capture-MS Homo sapiens
73 C6orf203  
Proximity Label-MS Homo sapiens
74 COX15 1355
Proximity Label-MS Homo sapiens
75 FASTKD5  
Proximity Label-MS Homo sapiens
76 SRP14 6727
Affinity Capture-MS Homo sapiens
77 PARK2  
Affinity Capture-MS Homo sapiens
78 MRPS34 65993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 ZBTB47  
Affinity Capture-MS Homo sapiens
80 PTCD3 55037
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 TMOD1  
Affinity Capture-MS Homo sapiens
83 TUFM 7284
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
84 ZBTB48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 TMEM43 79188
Co-fractionation Homo sapiens
86 HSCB 150274
Proximity Label-MS Homo sapiens
87 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
88 RPL35 11224
Affinity Capture-MS Homo sapiens
89 SRSF7 6432
Affinity Capture-MS Homo sapiens
90 DES 1674
Affinity Capture-MS Homo sapiens
91 MRPS18B 28973
Affinity Capture-MS Homo sapiens
92 NTRK1 4914
Affinity Capture-MS Homo sapiens
93 PRR4 11272
Affinity Capture-MS Homo sapiens
94 MRPS6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 CCDC109B 55013
Proximity Label-MS Homo sapiens
96 MOV10 4343
Affinity Capture-RNA Homo sapiens
97 ZMPSTE24 10269
Co-fractionation Homo sapiens
98 FBXL6  
Affinity Capture-MS Homo sapiens
99 LCN1 3933
Affinity Capture-MS Homo sapiens
100 RPS6 6194
Affinity Capture-MS Homo sapiens
101 MTFMT  
Proximity Label-MS Homo sapiens
102 MRPL11 65003
Proximity Label-MS Homo sapiens
103 MTRF1L  
Proximity Label-MS Homo sapiens
104 TMEM70  
Proximity Label-MS Homo sapiens
105 MRPS33  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 GLTSCR2  
Affinity Capture-MS Homo sapiens
107 MRPL2 51069
Affinity Capture-MS Homo sapiens
108 CHCHD1  
Proximity Label-MS Homo sapiens
109 RPF1  
Affinity Capture-MS Homo sapiens
110 CCDC59  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 TLX2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 OTC 5009
Proximity Label-MS Homo sapiens
113 MRRF  
Proximity Label-MS Homo sapiens
114 ABT1 29777
Affinity Capture-MS Homo sapiens
115 MRPS12  
Proximity Label-MS Homo sapiens
116 AURKAIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 DAP3 7818
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 DNAJC4  
Proximity Label-MS Homo sapiens
119 MRPS35 60488
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
120 RBM47 54502
Affinity Capture-MS Homo sapiens
121 YBX1 4904
Affinity Capture-MS Homo sapiens
122 MRPS11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 MTIF3  
Proximity Label-MS Homo sapiens
124 SRSF4 6429
Affinity Capture-MS Homo sapiens
125 EEF2 1938
Co-fractionation Homo sapiens
126 SRSF1 6426
Affinity Capture-MS Homo sapiens
127 USP36  
Affinity Capture-MS Homo sapiens
128 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 RPUSD3  
Proximity Label-MS Homo sapiens
130 RMND1 55005
Proximity Label-MS Homo sapiens
131 FAHD1 81889
Affinity Capture-MS Homo sapiens
132 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 DHX30 22907
Proximity Label-MS Homo sapiens
134 CORO1C 23603
Co-fractionation Homo sapiens
135 NXF1 10482
Affinity Capture-RNA Homo sapiens
136 SOX15  
Affinity Capture-MS Homo sapiens
137 C12orf65  
Proximity Label-MS Homo sapiens
138 MYCN  
Affinity Capture-MS Homo sapiens
139 PRR3  
Affinity Capture-MS Homo sapiens
140 CBX6  
Affinity Capture-MS Homo sapiens
141 TACO1  
Proximity Label-MS Homo sapiens
142 MTG1  
Proximity Label-MS Homo sapiens
143 MYC  
Affinity Capture-MS Homo sapiens
144 NOL12 79159
Affinity Capture-MS Homo sapiens
145 TSFM 10102
Proximity Label-MS Homo sapiens
146 ACAD9 28976
Proximity Label-MS Homo sapiens
147 RPL18 6141
Affinity Capture-MS Homo sapiens
148 VWA8 23078
Proximity Label-MS Homo sapiens
149 CLPB 81570
Proximity Label-MS Homo sapiens
150 GALNT2 2590
Co-fractionation Homo sapiens
151 MRPS17 51373
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 METTL15  
Proximity Label-MS Homo sapiens
153 ZC3H3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 UQCRFS1P1  
Co-fractionation Homo sapiens
155 MCUR1 63933
Proximity Label-MS Homo sapiens
156 FLOT1 10211
Co-fractionation Homo sapiens
157 ZNF263  
Affinity Capture-MS Homo sapiens
158 SOX2  
Proximity Label-MS Homo sapiens
159 ZNF574  
Affinity Capture-MS Homo sapiens
160 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 CLPP 8192
Proximity Label-MS Homo sapiens
162 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
163 ZNF707  
Affinity Capture-MS Homo sapiens
164 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
165 RIT1 6016
Negative Genetic Homo sapiens
166 RC3H1 149041
Affinity Capture-MS Homo sapiens
167 AUH 549
Proximity Label-MS Homo sapiens
168 MRPS2 51116
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 PDGFB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 ILF3 3609
Co-fractionation Homo sapiens
171 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 DNAJC19 131118
Proximity Label-MS Homo sapiens
173 MCAT 27349
Affinity Capture-MS Homo sapiens
174 TP53 7157
Affinity Capture-MS Homo sapiens
175 RPL6 6128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
177 APOBEC3D  
Affinity Capture-MS Homo sapiens
178 LONP1 9361
Proximity Label-MS Homo sapiens
179 MRPS18C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 MRPS31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 PDHA1 5160
Proximity Label-MS Homo sapiens
182 DNAJA3 9093
Proximity Label-MS Homo sapiens
183 SMURF1 57154
Affinity Capture-MS Homo sapiens
184 SQSTM1 8878
Proximity Label-MS Homo sapiens
185 MRPS15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 COX8A  
Proximity Label-MS Homo sapiens
187 MRPS10 55173
Co-fractionation Homo sapiens
188 ZNF764 92595
Affinity Capture-MS Homo sapiens
189 ZNF467  
Affinity Capture-MS Homo sapiens
190 ZNF331  
Affinity Capture-MS Homo sapiens
191 C21orf33  
Proximity Label-MS Homo sapiens
192 MRPL18 29074
Affinity Capture-MS Homo sapiens
193 SSBP1 6742
Proximity Label-MS Homo sapiens
194 KLF12  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 UFL1 23376
Affinity Capture-MS Homo sapiens
196 FASTKD3  
Proximity Label-MS Homo sapiens
197 NEIL1  
Affinity Capture-MS Homo sapiens
198 ACTA1 58
Affinity Capture-MS Homo sapiens
199 ZNF556 80032
Affinity Capture-MS Homo sapiens
200 SRSF3 6428
Affinity Capture-MS Homo sapiens
201 GFM1 85476
Proximity Label-MS Homo sapiens
202 AARS2  
Proximity Label-MS Homo sapiens
203 TEFM  
Proximity Label-MS Homo sapiens
204 MRPS9 64965
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 RPL23 9349
Co-fractionation Homo sapiens
206 SLC25A51  
Proximity Label-MS Homo sapiens
207 RPS8 6202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 TBRG4 9238
Proximity Label-MS Homo sapiens
209 TRMT10B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 GRSF1 2926
Proximity Label-MS Homo sapiens
211 C1QBP 708
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
212 GLI4  
Affinity Capture-MS Homo sapiens
213 KRAS 3845
Negative Genetic Homo sapiens
214 HNRNPU 3192
Affinity Capture-MS Homo sapiens
215 C17orf80 55028
Proximity Label-MS Homo sapiens
216 METTL17  
Proximity Label-MS Homo sapiens
217 MRPS22 56945
Affinity Capture-MS Homo sapiens
218 C8orf82  
Proximity Label-MS Homo sapiens
219 C19orf52  
Proximity Label-MS Homo sapiens
220 LUC7L 55692
Affinity Capture-MS Homo sapiens
221 DDX56  
Affinity Capture-MS Homo sapiens
222 DDX28