Gene description for MRPS17
Gene name mitochondrial ribosomal protein S17
Gene symbol MRPS17
Other names/aliases HSPC011
MRP-S17
RPMS17
S17mt
Species Homo sapiens
 Database cross references - MRPS17
ExoCarta ExoCarta_51373
Entrez Gene 51373
HGNC 14047
MIM 611980
UniProt Q9Y2R5  
 MRPS17 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for MRPS17
Molecular Function
    structural constituent of ribosome GO:0003735 NAS
    rRNA binding GO:0019843 IEA
Biological Process
    organelle organization GO:0006996 TAS
    mitochondrial translational elongation GO:0070125 TAS
    translation GO:0006412 NAS
    mitochondrial translational termination GO:0070126 TAS
    mitochondrial translation GO:0032543 TAS
    mitochondrial translational initiation GO:0070124 TAS
Subcellular Localization
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial small ribosomal subunit GO:0005763 NAS
 Experiment description of studies that identified MRPS17 in exosomes
1
Experiment ID 191
ISEV standards
✘ EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MRPS17
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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