Gene description for SLIRP
Gene name SRA stem-loop interacting RNA binding protein
Gene symbol SLIRP
Other names/aliases C14orf156
DC50
PD04872
Species Homo sapiens
 Database cross references - SLIRP
ExoCarta ExoCarta_81892
Vesiclepedia VP_81892
Entrez Gene 81892
HGNC 20495
MIM 610211
UniProt Q9GZT3  
 SLIRP identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for SLIRP
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Biological Process
    negative regulation of mitochondrial RNA catabolic process GO:0000961 IEA
    mitochondrion organization GO:0007005 IEA
    spermatid development GO:0007286 IEA
    single fertilization GO:0007338 IEA
    flagellated sperm motility GO:0030317 IEA
Subcellular Localization
    acrosomal vesicle GO:0001669 IEA
    nucleus GO:0005634 IEA
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 IDA
    mitochondrial matrix GO:0005759 TAS
    sperm flagellum GO:0036126 IEA
    perinuclear region of cytoplasm GO:0048471 IEA
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified SLIRP in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for SLIRP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 MRPS27 23107
Proximity Label-MS Homo sapiens
3 AFG3L2 10939
Proximity Label-MS Homo sapiens
4 PYCR2 29920
Proximity Label-MS Homo sapiens
5 IGF2BP1 10642
Proximity Label-MS Homo sapiens
6 PQBP1  
Co-fractionation Homo sapiens
7 PMPCA 23203
Proximity Label-MS Homo sapiens
8 MRPL48  
Proximity Label-MS Homo sapiens
9 RBPMS 11030
Two-hybrid Homo sapiens
10 MRPS18B 28973
Proximity Label-MS Homo sapiens
11 Cdh1 12550
Affinity Capture-MS Mus musculus
12 RIN3  
Affinity Capture-MS Homo sapiens
13 MRPS10 55173
Proximity Label-MS Homo sapiens
14 ADRB2  
Affinity Capture-MS Homo sapiens
15 FASTKD5  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
16 MTG2  
Proximity Label-MS Homo sapiens
17 NGRN  
Proximity Label-MS Homo sapiens
18 ARHGAP42  
Affinity Capture-MS Homo sapiens
19 MRPL10 124995
Proximity Label-MS Homo sapiens
20 ETFB 2109
Proximity Label-MS Homo sapiens
21 CSNK2A1 1457
Biochemical Activity Homo sapiens
22 MRPL50 54534
Proximity Label-MS Homo sapiens
23 PNMAL1  
Affinity Capture-MS Homo sapiens
24 HNRNPR 10236
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
25 MRRF  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
26 PDHB 5162
Proximity Label-MS Homo sapiens
27 MRPL49 740
Proximity Label-MS Homo sapiens
28 MRPL44  
Proximity Label-MS Homo sapiens
29 CCDC102B  
Two-hybrid Homo sapiens
30 MTRF1  
Proximity Label-MS Homo sapiens
31 SBDS 51119
Co-fractionation Homo sapiens
32 CCDC90B  
Proximity Label-MS Homo sapiens
33 ALAS1  
Proximity Label-MS Homo sapiens
34 LRPPRC 10128
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 WTAP 9589
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
36 TRUB2  
Proximity Label-MS Homo sapiens
37 PLEKHG4  
Affinity Capture-MS Homo sapiens
38 ATP5D 513
Proximity Label-MS Homo sapiens
39 SNRNP70 6625
Co-fractionation Homo sapiens
40 MRPL20 55052
Proximity Label-MS Homo sapiens
41 NDUFS3 4722
Proximity Label-MS Homo sapiens
42 B3GNT2 10678
Affinity Capture-MS Homo sapiens
43 OGDH 4967
Proximity Label-MS Homo sapiens
44 TFAM 7019
Proximity Label-MS Homo sapiens
45 MRPS31  
Proximity Label-MS Homo sapiens
46 KIF23 9493
Affinity Capture-MS Homo sapiens
47 C8orf82  
Proximity Label-MS Homo sapiens
48 NDUFA7 4701
Proximity Label-MS Homo sapiens
49 WDR83  
Affinity Capture-MS Homo sapiens
50 MRPS36 92259
Proximity Label-MS Homo sapiens
51 MRPS5 64969
Proximity Label-MS Homo sapiens
52 HINT2 84681
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
53 MRPS23 51649
Proximity Label-MS Homo sapiens
54 MRPS24 64951
Proximity Label-MS Homo sapiens
55 COA3 28958
Affinity Capture-Western Homo sapiens
56 CALM3 808
Affinity Capture-MS Homo sapiens
57 SNRPC 6631
Co-fractionation Homo sapiens
58 ETFA 2108
Proximity Label-MS Homo sapiens
59 C11orf74  
Affinity Capture-MS Homo sapiens
60 MTUS2 23281
Two-hybrid Homo sapiens
61 MYCN  
Affinity Capture-MS Homo sapiens
62 Cenpe  
Affinity Capture-MS Mus musculus
63 KRT31 3881
Two-hybrid Homo sapiens
64 POLRMT 5442
Proximity Label-MS Homo sapiens
65 Kctd5  
Affinity Capture-MS Mus musculus
66 EXD2  
Proximity Label-MS Homo sapiens
67 ERAL1  
Proximity Label-MS Homo sapiens
68 DGCR2 9993
Affinity Capture-MS Homo sapiens
69 NDUFV1 4723
Proximity Label-MS Homo sapiens
70 MRPL55  
Proximity Label-MS Homo sapiens
71 MRPL42  
Proximity Label-MS Homo sapiens
72 NDUFV3 4731
Proximity Label-MS Homo sapiens
73 MRPS7 51081
Proximity Label-MS Homo sapiens
74 SSBP1 6742
Proximity Label-MS Homo sapiens
75 BCS1L 617
Proximity Label-MS Homo sapiens
76 PMPCB 9512
Proximity Label-MS Homo sapiens
77 TACO1  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
78 FASTKD2  
Proximity Label-MS Homo sapiens
79 NME4 4833
Proximity Label-MS Homo sapiens
80 NDUFA6  
Proximity Label-MS Homo sapiens
81 VWA8 23078
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
82 ARHGAP9 64333
Affinity Capture-MS Homo sapiens
83 PABPC4 8761
Affinity Capture-MS Homo sapiens
84 MTERF3  
Proximity Label-MS Homo sapiens
85 RBM8A 9939
Co-fractionation Homo sapiens
86 KIF14 9928
Affinity Capture-MS Homo sapiens
87 DMRTB1  
Two-hybrid Homo sapiens
88 MCF2L2 23101
Affinity Capture-MS Homo sapiens
89 PAM16  
Proximity Label-MS Homo sapiens
90 GOLGA6L9  
Two-hybrid Homo sapiens
91 MRPS30 10884
Proximity Label-MS Homo sapiens
92 RFX5 5993
Co-fractionation Homo sapiens
93 HAUS2  
Affinity Capture-MS Homo sapiens
94 IPO8 10526
Proximity Label-MS Homo sapiens
95 C6orf203  
Proximity Label-MS Homo sapiens
96 NDUFS4 4724
Proximity Label-MS Homo sapiens
97 ARHGEF39 84904
Affinity Capture-MS Homo sapiens
98 MRPL4 51073
Proximity Label-MS Homo sapiens
99 FHL3 2275
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 MRPL45 84311
Proximity Label-MS Homo sapiens
101 MRPS26 64949
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
102 MRPS34 65993
Proximity Label-MS Homo sapiens
103 STOML2 30968
Proximity Label-MS Homo sapiens
104 ACOT2 10965
Proximity Label-MS Homo sapiens
105 RBM7  
Proximity Label-MS Homo sapiens
106 TUFM 7284
Proximity Label-MS Homo sapiens
107 LETM1 3954
Proximity Label-MS Homo sapiens
108 PTCD3 55037
Proximity Label-MS Homo sapiens
109 HSCB 150274
Proximity Label-MS Homo sapiens
110 ESRRB  
Affinity Capture-MS Homo sapiens
111 NDUFS8 4728
Proximity Label-MS Homo sapiens
112 CDH1 999
Affinity Capture-MS Homo sapiens
113 MMAB 326625
Proximity Label-MS Homo sapiens
114 CST2  
Affinity Capture-MS Homo sapiens
115 ORC2  
Affinity Capture-MS Homo sapiens
116 VCP 7415
Affinity Capture-MS Homo sapiens
117 MRPS6  
Proximity Label-MS Homo sapiens
118 CCDC109B 55013
Proximity Label-MS Homo sapiens
119 HNRNPAB 3182
Proximity Label-MS Homo sapiens
120 CTNNB1 1499
Affinity Capture-MS Homo sapiens
121 TBRG4 9238
Proximity Label-MS Homo sapiens
122 RBM11  
Proximity Label-MS Homo sapiens
123 MTPAP 55149
Proximity Label-MS Homo sapiens
124 EIF4G2 1982
Co-fractionation Homo sapiens
125 MTFMT  
Proximity Label-MS Homo sapiens
126 RNMTL1  
Proximity Label-MS Homo sapiens
127 MRPL11 65003
Proximity Label-MS Homo sapiens
128 MTRF1L  
Proximity Label-MS Homo sapiens
129 DDX39B 7919
Proximity Label-MS Homo sapiens
130 TMEM70  
Proximity Label-MS Homo sapiens
131 MRPS14  
Proximity Label-MS Homo sapiens
132 MRPS33  
Proximity Label-MS Homo sapiens
133 MRPL41 64975
Proximity Label-MS Homo sapiens
134 ZCCHC8 55596
Proximity Label-MS Homo sapiens
135 HNRNPDL 9987
Proximity Label-MS Homo sapiens
136 CTNNA2 1496
Affinity Capture-MS Homo sapiens
137 NFS1 9054
Proximity Label-MS Homo sapiens
138 ASB5  
Affinity Capture-MS Homo sapiens
139 MRPL12 6182
Proximity Label-MS Homo sapiens
140 ACAT1 38
Proximity Label-MS Homo sapiens
141 MRPL21 219927
Proximity Label-MS Homo sapiens
142 SUGP1  
Co-fractionation Homo sapiens
143 MRPS12  
Proximity Label-MS Homo sapiens
144 MTIF2 4528
Proximity Label-MS Homo sapiens
145 TRMT10C 54931
Proximity Label-MS Homo sapiens
146 PNPT1 87178
Proximity Label-MS Homo sapiens
147 ATP5F1 515
Proximity Label-MS Homo sapiens
148 NDUFA9 4704
Proximity Label-MS Homo sapiens
149 RC3H2  
Affinity Capture-MS Homo sapiens
150 NDUFV2 4729
Proximity Label-MS Homo sapiens
151 MRPS11  
Proximity Label-MS Homo sapiens
152 MTIF3  
Proximity Label-MS Homo sapiens
153 ARVCF 421
Affinity Capture-MS Homo sapiens
154 AURKA 6790
Affinity Capture-MS Homo sapiens
155 MRPL27 51264
Proximity Label-MS Homo sapiens
156 MRPL9 65005
Proximity Label-MS Homo sapiens
157 U2AF2 11338
Co-fractionation Homo sapiens
158 SLC30A9 10463
Proximity Label-MS Homo sapiens
159 GLS 2744
Proximity Label-MS Homo sapiens
160 SLX1B  
Affinity Capture-MS Homo sapiens
161 RMND1 55005
Proximity Label-MS Homo sapiens
162 ECHDC2 55268
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 PYCR1 5831
Proximity Label-MS Homo sapiens
164 ELAC2 60528
Proximity Label-MS Homo sapiens
165 GADD45GIP1  
Affinity Capture-MS Homo sapiens
166 DHX30 22907
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
167 VARS2  
Proximity Label-MS Homo sapiens
168 HNRNPUL1 11100
Proximity Label-MS Homo sapiens
169 PDCD11 22984
Proximity Label-MS Homo sapiens
170 ECHS1 1892
Proximity Label-MS Homo sapiens
171 KRT27 342574
Two-hybrid Homo sapiens
172 C17orf80 55028
Proximity Label-MS Homo sapiens
173 MRPL47 57129
Proximity Label-MS Homo sapiens
174 MRPS28  
Proximity Label-MS Homo sapiens
175 C12orf65  
Proximity Label-MS Homo sapiens
176 CDC25C  
Affinity Capture-MS Homo sapiens
177 BIRC6 57448
Affinity Capture-MS Homo sapiens
178 MRPL52  
Proximity Label-MS Homo sapiens
179 CST4 1472
Affinity Capture-MS Homo sapiens
180 MRPL19 9801
Proximity Label-MS Homo sapiens
181 DKC1 1736
Proximity Label-MS Homo sapiens
182 RPUSD4 84881
Proximity Label-MS Homo sapiens
183 MYC  
Affinity Capture-MS Homo sapiens
184 PKN1 5585
Affinity Capture-MS Homo sapiens
185 NDUFA2 4695
Proximity Label-MS Homo sapiens
186 ZFR 51663
Proximity Label-MS Homo sapiens
187 MRPL37 51253
Proximity Label-MS Homo sapiens
188 DLST 1743
Proximity Label-MS Homo sapiens
189 TSFM 10102
Proximity Label-MS Homo sapiens
190 DAP3 7818
Proximity Label-MS Homo sapiens
191 SIRT1  
Proximity Label-MS Homo sapiens
192 KRT40  
Two-hybrid Homo sapiens
193 ACAD9 28976
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
194 DSTN 11034
Co-fractionation Homo sapiens
195 NDUFS1 4719
Proximity Label-MS Homo sapiens
196 AMOT 154796
Two-hybrid Homo sapiens
197 DDRGK1 65992
Affinity Capture-MS Homo sapiens
198 LAMA4 3910
Co-fractionation Homo sapiens
199 CTNNA1 1495
Affinity Capture-MS Homo sapiens
200 MRPS17 51373
Proximity Label-MS Homo sapiens
201 MRPL38  
Proximity Label-MS Homo sapiens
202 DLAT 1737
Proximity Label-MS Homo sapiens
203 SMYD1  
Affinity Capture-MS Homo sapiens
204 METTL15  
Proximity Label-MS Homo sapiens
205 ARHGEF40 55701
Affinity Capture-MS Homo sapiens
206 MCUR1 63933
Proximity Label-MS Homo sapiens
207 NDUFS2 4720
Proximity Label-MS Homo sapiens
208 HUWE1 10075
Affinity Capture-MS Homo sapiens
209 PIN4 5303
Co-fractionation Homo sapiens
210 PPIF 10105
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
211 MUC7 4589
Affinity Capture-MS Homo sapiens
212 GFM2 84340
Proximity Label-MS Homo sapiens
213 DBT 1629
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 CLPP 8192
Proximity Label-MS Homo sapiens
215 STARD8  
Affinity Capture-MS Homo sapiens
216 CS 1431
Proximity Label-MS Homo sapiens
217 ARHGEF18 23370
Affinity Capture-MS Homo sapiens
218 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
219 METTL17  
Proximity Label-MS Homo sapiens
220 AUH 549
Proximity Label-MS Homo sapiens
221 NDUFAF2  
Proximity Label-MS Homo sapiens
222 MRPS9 64965
Proximity Label-MS Homo sapiens
223 ILF3 3609
Co-fractionation Homo sapiens
224 MRPL22  
Proximity Label-MS Homo sapiens
225 ATP5J 522
Proximity Label-MS Homo sapiens
226 MRPS2 51116
Proximity Label-MS Homo sapiens
227 Atp7a  
Affinity Capture-MS Mus musculus
228 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
229 CARS2 79587
Proximity Label-MS Homo sapiens
230 LONP1 9361
Proximity Label-MS Homo sapiens
231 SF3B4 10262
Co-fractionation Homo sapiens
232 MRPS18C  
Proximity Label-MS Homo sapiens
233 MRPL53  
Proximity Label-MS Homo sapiens
234 MRPL43 84545
Proximity Label-MS Homo sapiens
235 HNRNPA2B1 3181
Co-fractionation Homo sapiens
236 PDHA1 5160
Proximity Label-MS Homo sapiens
237 MRPS35 60488
Proximity Label-MS Homo sapiens
238 SQSTM1 8878
Co-fractionation Homo sapiens
239 NDUFAF4 29078
Proximity Label-MS Homo sapiens
240 NDUFA12 55967
Proximity Label-MS Homo sapiens
241 ELAVL1 1994
Co-fractionation Homo sapiens
242 MDH2 4191
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
243 PNMA1 9240
Two-hybrid Homo sapiens
244 SUCLA2 8803
Proximity Label-MS Homo sapiens
245 SHMT2 6472
Proximity Label-MS Homo sapiens
246 C21orf33  
Proximity Label-MS Homo sapiens
247 HNRNPK 3190
Proximity Label-MS Homo sapiens
248 CCT7 10574
Co-fractionation Homo sapiens
249 BABAM1 29086
Affinity Capture-MS Homo sapiens
250 ZG16B 124220
Affinity Capture-MS Homo sapiens
251 FASTKD3  
Proximity Label-MS Homo sapiens
252 NDUFAF3 25915
Proximity Label-MS Homo sapiens
253 PREPL 9581
Affinity Capture-MS Homo sapiens
254 NDUFA5 4698
Proximity Label-MS Homo sapiens
255 RPL38 6169
Co-fractionation Homo sapiens
256 GFM1 85476
Proximity Label-MS Homo sapiens
257 HNRNPL 3191
Proximity Label-MS Homo sapiens
258 ARHGAP36  
Affinity Capture-MS Homo sapiens
259 STK40  
Two-hybrid Homo sapiens
260 TEFM  
Proximity Label-MS Homo sapiens
261 ACOT1 641371
Proximity Label-MS Homo sapiens
262 IBA57  
Proximity Label-MS Homo sapiens
263 MRPL46  
Proximity Label-MS Homo sapiens
264 RPUSD3  
Proximity Label-MS Homo sapiens
265 PHACTR3  
Affinity Capture-MS Homo sapiens
266 CIT 11113
Affinity Capture-MS Homo sapiens
267 MRPS16  
Proximity Label-MS Homo sapiens
268 GRSF1 2926
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
269 C1QBP 708
Proximity Label-MS Homo sapiens
270 XRCC6 2547
Co-fractionation Homo sapiens
271 MRPS21  
Proximity Label-MS Homo sapiens
272 PTGES3 10728
Affinity Capture-MS Homo sapiens
273 EID1  
Affinity Capture-MS Homo sapiens
274 C9orf72  
Affinity Capture-MS Homo sapiens
275 AR 367
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
276 MRPS25 64432
Proximity Label-MS Homo sapiens
277 RC3H1 149041
Affinity Capture-MS Homo sapiens
278 MRPS22 56945
Proximity Label-MS Homo sapiens
279 TIMM44 10469
Proximity Label-MS Homo sapiens
280 MRPL28 10573
Proximity Label-MS Homo sapiens
281 SCAMP3 10067
Co-fractionation Homo sapiens
282 NDUFS6  
Proximity Label-MS Homo sapiens
283 DDX28  
Proximity Label-MS Homo sapiens
284 IARS2 55699
Proximity Label-MS Homo sapiens
285 EXOSC8  
Two-hybrid Homo sapiens
286 NDUFS7 374291
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SLIRP is involved
PathwayEvidenceSource
Metabolism of RNA TAS Reactome
Mitochondrial RNA degradation TAS Reactome





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