Gene description for MUC7
Gene name mucin 7, secreted
Gene symbol MUC7
Other names/aliases MG2
Species Homo sapiens
 Database cross references - MUC7
ExoCarta ExoCarta_4589
Entrez Gene 4589
HGNC 7518
MIM 158375
UniProt Q8TAX7  
 MUC7 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for MUC7
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein O-linked glycosylation GO:0006493 TAS
    cellular protein metabolic process GO:0044267 TAS
    O-glycan processing GO:0016266 TAS
    post-translational protein modification GO:0043687 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    Golgi lumen GO:0005796 TAS
 Experiment description of studies that identified MUC7 in exosomes
1
Experiment ID 66
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for MUC7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SELL 6402
Reconstituted Complex Homo sapiens
2 LTF 4057
Affinity Capture-MS Homo sapiens
Far Western Homo sapiens
3 GALNT14  
Biochemical Activity Homo sapiens
View the network image/svg+xml
 Pathways in which MUC7 is involved
PathwayEvidenceSource
O-linked glycosylation of mucins TAS Reactome
Termination of O-glycan biosynthesis TAS Reactome





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