Gene description for ARVCF
Gene name armadillo repeat gene deleted in velocardiofacial syndrome
Gene symbol ARVCF
Other names/aliases -
Species Homo sapiens
 Database cross references - ARVCF
ExoCarta ExoCarta_421
Vesiclepedia VP_421
Entrez Gene 421
HGNC 728
MIM 602269
UniProt O00192  
 ARVCF identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 17956143    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for ARVCF
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    single organismal cell-cell adhesion GO:0016337 IEA
    multicellular organismal development GO:0007275 IEA
    calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339 IEA
    cell adhesion GO:0007155 TAS
Subcellular Localization
    cell junction GO:0030054 IDA
    nucleoplasm GO:0005654 IDA
    intracellular GO:0005622 TAS
    cytoplasm GO:0005737 IEA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified ARVCF in exosomes
1
Experiment ID 20
MISEV standards
EM
EV Biophysical techniques
HSP90|CD63|CD81|LAMP1
EV Enriched markers
GOLGA2|cytochrome c
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
2
Experiment ID 211
MISEV standards
EM
EV Biophysical techniques
TSG101|Alix|EpCAM|TFRC
EV Enriched markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 212
MISEV standards
CEM
EV Biophysical techniques
TSG101|Alix|EpCAM|TFRC
EV Enriched markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARVCF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDH15 1013
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
2 ERBB2IP 55914
Invivo Homo sapiens
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which ARVCF is involved
No pathways found





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