Experiment description of studies that identified CTDSPL in sEVs

1 Experiment ID 231 MISEV standards ✘ Biophysical techniques ✔ Alix|CD63|CD9 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Lipids Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 232 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 233 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 63 MISEV standards ✘ Biophysical techniques ✔ AQP2 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 19056867     Organism Homo sapiens Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes. Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA" Journal name JASN Publication year 2009 Sample Urine Sample name Urine - Normal Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting

Protein-protein interactions for CTDSPL

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SLC29A1 2030 Proximity Label-MS Homo sapiens 2 CLCN7 1186 Proximity Label-MS Homo sapiens 3 ZDHHC5 25921 Proximity Label-MS Homo sapiens 4 RFTN1 23180 Proximity Label-MS Homo sapiens 5 CEP89 84902 Proximity Label-MS Homo sapiens 6 ARHGAP39   Proximity Label-MS Homo sapiens 7 TBC1D4   Affinity Capture-MS Homo sapiens 8 ADGRL2 23266 Proximity Label-MS Homo sapiens 9 DTNA   Proximity Label-MS Homo sapiens 10 ROBO1 6091 Proximity Label-MS Homo sapiens 11 FMN2   Proximity Label-MS Homo sapiens 12 BASP1 10409 Proximity Label-MS Homo sapiens 13 SLC12A2 6558 Proximity Label-MS Homo sapiens 14 USP31 57478 Proximity Label-MS Homo sapiens 15 CADM1 23705 Proximity Label-MS Homo sapiens 16 CTDSP2 10106 Affinity Capture-MS Homo sapiens 17 SLC39A10 57181 Proximity Label-MS Homo sapiens 18 NUMBL 9253 Proximity Label-MS Homo sapiens 19 PACS1 55690 Proximity Label-MS Homo sapiens 20 TIAM1   Proximity Label-MS Homo sapiens 21 MBP 4155 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens 22 TULP3 7289 Proximity Label-MS Homo sapiens 23 PTPN14 5784 Proximity Label-MS Homo sapiens 24 PALM 5064 Proximity Label-MS Homo sapiens 25 ESYT2 57488 Proximity Label-MS Homo sapiens 26 SLC12A7 10723 Proximity Label-MS Homo sapiens 27 TMEM2 23670 Proximity Label-MS Homo sapiens 28 GPRIN1 114787 Proximity Label-MS Homo sapiens 29 SLC30A1 7779 Proximity Label-MS Homo sapiens 30 NF2 4771 Proximity Label-MS Homo sapiens 31 ITGA6 3655 Proximity Label-MS Homo sapiens 32 CXADR 1525 Proximity Label-MS Homo sapiens 33 C2CD4C   Proximity Label-MS Homo sapiens 34 MCAM 4162 Proximity Label-MS Homo sapiens 35 EFR3B   Proximity Label-MS Homo sapiens 36 CNNM3 26505 Proximity Label-MS Homo sapiens 37 ADD2 119 Proximity Label-MS Homo sapiens 38 NUMB 8650 Proximity Label-MS Homo sapiens 39 RELL1 768211 Proximity Label-MS Homo sapiens 40 ARL13B 200894 Proximity Label-MS Homo sapiens 41 CDC42EP1 11135 Proximity Label-MS Homo sapiens 42 TTC7B 145567 Proximity Label-MS Homo sapiens 43 CACHD1   Proximity Label-MS Homo sapiens 44 PALM2   Proximity Label-MS Homo sapiens 45 MARVELD2 153562 Proximity Label-MS Homo sapiens 46 FLVCR1 28982 Proximity Label-MS Homo sapiens 47 FAM129B 64855 Proximity Label-MS Homo sapiens 48 CDCA3 83461 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens 49 SLC39A6 25800 Proximity Label-MS Homo sapiens 50 ATP2B1 490 Proximity Label-MS Homo sapiens 51 ARVCF 421 Proximity Label-MS Homo sapiens 52 TBC1D10B 26000 Proximity Label-MS Homo sapiens 53 FAM171A1 221061 Proximity Label-MS Homo sapiens 54 TJP1 7082 Proximity Label-MS Homo sapiens 55 DAB2IP 153090 Proximity Label-MS Homo sapiens 56 EGFR 1956 Proximity Label-MS Homo sapiens 57 PCDH7 5099 Proximity Label-MS Homo sapiens 58 KCNE3   Affinity Capture-MS Homo sapiens 59 FGFR2 2263 Two-hybrid Homo sapiens 60 SLC3A2 6520 Proximity Label-MS Homo sapiens 61 AKAP5   Proximity Label-MS Homo sapiens 62 ABCC1 4363 Proximity Label-MS Homo sapiens 63 MPZL1 9019 Proximity Label-MS Homo sapiens 64 CTNNA1 1495 Proximity Label-MS Homo sapiens 65 CCDC8   Proximity Label-MS Homo sapiens 66 MAGEA8   Affinity Capture-MS Homo sapiens 67 GPRIN3   Proximity Label-MS Homo sapiens 68 KIAA1549   Proximity Label-MS Homo sapiens 69 ITGA5 3678 Proximity Label-MS Homo sapiens 70 PVRL2 5819 Proximity Label-MS Homo sapiens 71 PSD3 23362 Proximity Label-MS Homo sapiens 72 CTDSP1 58190 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 73 SNAI1   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 74 ATP2B4 493 Proximity Label-MS Homo sapiens 75 SPTBN2 6712 Proximity Label-MS Homo sapiens 76 FAM171B   Proximity Label-MS Homo sapiens 77 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 78 KIRREL 55243 Proximity Label-MS Homo sapiens 79 PPP1R9A   Proximity Label-MS Homo sapiens 80 MICAL3 57553 Proximity Label-MS Homo sapiens 81 SLC38A1 81539 Proximity Label-MS Homo sapiens 82 EPHA2 1969 Proximity Label-MS Homo sapiens 83 ANK3   Proximity Label-MS Homo sapiens 84 CD44 960 Proximity Label-MS Homo sapiens 85 HSPA12A 259217 Proximity Label-MS Homo sapiens 86 NOTCH1 4851 Proximity Label-MS Homo sapiens 87 CTNND1 1500 Proximity Label-MS Homo sapiens View the network

Pathways in which CTDSPL is involved

No pathways found