Gene description for NUMB
Gene name	numb homolog (Drosophila)
Gene symbol	NUMB
Other names/aliases	C14orf41 S171 c14_5527
Species	Homo sapiens
Database cross references - NUMB
ExoCarta	ExoCarta_8650
Entrez Gene	8650
HGNC	8060
MIM	603728
UniProt	P49757
NUMB identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for NUMB

Molecular Function     protein binding GO:0005515 IPI     alpha-catenin binding GO:0045294 IEA     cadherin binding GO:0045296 IEA     beta-catenin binding GO:0008013 IEA Biological Process     Notch signaling pathway GO:0007219 TAS     positive regulation of polarized epithelial cell differentiation GO:0030862 IEA     lung epithelial cell differentiation GO:0060487 IEA     negative regulation of Notch signaling pathway GO:0045746 IEA     negative regulation of protein localization to plasma membrane GO:1903077 IMP     axon guidance GO:0007411 TAS     lateral ventricle development GO:0021670 ISS     positive regulation of cell migration GO:0030335 IMP     positive regulation of neurogenesis GO:0050769 ISS     adherens junction organization GO:0034332 IEA     neuroblast division in subventricular zone GO:0021849 ISS Subcellular Localization     extrinsic component of plasma membrane GO:0019897 IEA     plasma membrane GO:0005886 TAS     early endosome GO:0005769 IEA     clathrin-coated vesicle GO:0030136 IDA     integral component of plasma membrane GO:0005887 TAS     basolateral plasma membrane GO:0016323 IEA     focal adhesion GO:0005925 IDA     apical part of cell GO:0045177 IEA     nucleus GO:0005634 IEA