Gene description for Flnb
Gene name filamin, beta
Gene symbol Flnb
Other names/aliases AL024016
Fln-b
Species Mus musculus
 Database cross references - Flnb
ExoCarta ExoCarta_286940
Entrez Gene 286940
UniProt Q80X90  
 Flnb identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Flnb
Molecular Function
    identical protein binding GO:0042802 ISO
    actin binding GO:0003779 IEA
    poly(A) RNA binding GO:0044822 ISO
    protein binding GO:0005515 IPI
Biological Process
    keratinocyte development GO:0003334 IMP
    cell differentiation GO:0030154 IEA
    epithelial cell morphogenesis GO:0003382 IMP
    skeletal muscle tissue development GO:0007519 IDA
    actin cytoskeleton organization GO:0030036 IMP
Subcellular Localization
    cytoplasm GO:0005737 ISO
    cytoskeleton GO:0005856 IEA
    focal adhesion GO:0005925 ISO
    plasma membrane GO:0005886 ISO
    brush border GO:0005903 IDA
    stress fiber GO:0001725 IDA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Flnb in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Flnb
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Flnb is involved
PathwayEvidenceSource
ISG15 antiviral mechanism IEA Reactome





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