Gene description for BMP2K
Gene name BMP2 inducible kinase
Gene symbol BMP2K
Other names/aliases BIKE
HRIHFB2017
Species Homo sapiens
 Database cross references - BMP2K
ExoCarta ExoCarta_55589
Vesiclepedia VP_55589
Entrez Gene 55589
HGNC 18041
UniProt Q9NSY1  
 BMP2K identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for BMP2K
Molecular Function
    ATP binding GO:0005524 IEA
    phosphatase regulator activity GO:0019208 IEA
    protein serine/threonine kinase activity GO:0004674 IEA
Biological Process
    regulation of bone mineralization GO:0030500 IEA
    protein phosphorylation GO:0006468 IEA
    regulation of catalytic activity GO:0050790 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified BMP2K in exosomes
1
Experiment ID 834
MISEV standards
EM
EV Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
EV Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for BMP2K
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which BMP2K is involved
No pathways found





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