Gene description for SYNPO
Gene name synaptopodin
Gene symbol SYNPO
Other names/aliases -
Species Homo sapiens
 Database cross references - SYNPO
ExoCarta ExoCarta_11346
Entrez Gene 11346
HGNC 30672
MIM 608155
UniProt Q8N3V7  
 SYNPO identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for SYNPO
Molecular Function
    protein binding GO:0005515 IPI
    actin binding GO:0003779 ISS
Biological Process
    regulation of stress fiber assembly GO:0051492 ISS
    positive regulation of actin filament bundle assembly GO:0032233 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    stress fiber GO:0001725 IEA
    actin cytoskeleton GO:0015629 ISS
    postsynaptic membrane GO:0045211 IEA
    perikaryon GO:0043204 IEA
    dendritic spine GO:0043197 TAS
    postsynaptic density GO:0014069 IEA
    bicellular tight junction GO:0005923 IEA
 Experiment description of studies that identified SYNPO in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for SYNPO
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAGI1  
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which SYNPO is involved
No pathways found





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