Gene description for ZBTB20
Gene name zinc finger and BTB domain containing 20
Gene symbol ZBTB20
Other names/aliases DPZF
HOF
ODA-8S
PRIMS
ZNF288
Species Homo sapiens
 Database cross references - ZBTB20
ExoCarta ExoCarta_26137
Entrez Gene 26137
HGNC 13503
MIM 606025
UniProt Q9HC78  
 ZBTB20 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ZBTB20
Molecular Function
    metal ion binding GO:0046872 IEA
    DNA binding GO:0003677 IEA
    RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription GO:0001078 IEA
Biological Process
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified ZBTB20 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ZBTB20
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZBTB20 is involved
No pathways found





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