|
 Gene description for ARHGEF17 |
| Gene name |
Rho guanine nucleotide exchange factor (GEF) 17 |
| Gene symbol |
ARHGEF17 |
| Other names/aliases |
P164RHOGEF
TEM4
p164-RhoGEF |
| Species |
Homo sapiens |
| Database cross references - ARHGEF17 |
| ExoCarta |
ExoCarta_9828 |
| Entrez Gene |
9828 |
| HGNC |
21726 |
| UniProt |
Q96PE2
|
| ARHGEF17 identified in exosomes derived from the following tissue/cell type |
|
Liver cancer cells
|
25265333
|
|
Liver cancer cells
|
25265333
|
| Gene ontology annotations for ARHGEF17 |
|
|
| Experiment description of studies that identified ARHGEF17 in exosomes |
| 1 |
| Experiment ID |
266 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✔
TSG101|Alix
|
EV Cytosolic markers |
|
✘
|
EV Membrane markers |
|
✔
CANX|HSP90B1
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
25265333
|
| Organism |
Homo sapiens |
| Experiment description |
Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh‑7 Cells Using SILAC Labeling and LC−MS/MS |
| Authors |
Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J |
| Journal name |
J Proteome Res
|
| Publication year |
2014 |
| Sample |
Liver cancer cells |
| Sample name |
Huh-7 - Wild type |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| 2 |
| Experiment ID |
268 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✔
TSG101|Alix
|
EV Cytosolic markers |
|
✘
|
EV Membrane markers |
|
✔
CANX|HSP90B1
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
25265333
|
| Organism |
Homo sapiens |
| Experiment description |
Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh‑7 Cells Using SILAC Labeling and LC−MS/MS |
| Authors |
Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J |
| Journal name |
J Proteome Res
|
| Publication year |
2014 |
| Sample |
Liver cancer cells |
| Sample name |
Huh-7 - Transfected with HBx-null HBV replicon plasmids |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| Protein-protein interactions for ARHGEF17 |
|
|
| Pathways in which ARHGEF17 is involved |
|
|
|
