Gene ontology annotations for CPM |
|
Experiment description of studies that identified CPM in exosomes |
1 |
Experiment ID |
211 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix
|
EV Cytosolic markers |
✔
EpCAM|TFRC
|
EV Membrane markers |
✔
cytochrome c|GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23333927
|
Organism |
Homo sapiens |
Experiment description |
Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors |
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year |
2013 |
Sample |
Ovarian cancer cells |
Sample name |
IGROV1 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.09-1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
2 |
Experiment ID |
212 |
ISEV standards |
✔
CEM
|
EV Biophysical techniques |
✔
TSG101|Alix
|
EV Cytosolic markers |
✔
EpCAM|TFRC
|
EV Membrane markers |
✔
Cytochrome C|GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23333927
|
Organism |
Homo sapiens |
Experiment description |
Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors |
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year |
2013 |
Sample |
Ovarian cancer cells |
Sample name |
OVCAR-3 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.09-1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
3 |
Experiment ID |
275 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix|RAB5A
|
EV Cytosolic markers |
✔
CD9|CD82|CD63|CD81
|
EV Membrane markers |
✔
AIF
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25844599
|
Organism |
Homo sapiens |
Experiment description |
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors |
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year |
2015 |
Sample |
Prostate cancer cells |
Sample name |
DU145 - Docetaxel sensitive |
Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.12-1.19 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry/Flow cytometry/Western blotting |
|
|
4 |
Experiment ID |
274 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix|RAB5A
|
EV Cytosolic markers |
✔
CD9|CD82|CD63|CD81
|
EV Membrane markers |
✔
AIF
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25844599
|
Organism |
Homo sapiens |
Experiment description |
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors |
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year |
2015 |
Sample |
Prostate cancer cells |
Sample name |
DU145 - Docetaxel resistant |
Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.13-1.18 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry Flow cytometry Western blotting |
|
|
5 |
Experiment ID |
193 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
CD63|CD9
|
EV Membrane markers |
✔
PHB
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
21595033
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year |
2011 |
Sample |
Urine |
Sample name |
Urine - Normal |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
6 |
Experiment ID |
194 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
21595033
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year |
2011 |
Sample |
Urine |
Sample name |
Urine - Patients of basement membrane nephropathy |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
7 |
Experiment ID |
195 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
21595033
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year |
2011 |
Sample |
Urine |
Sample name |
Urine - Patients of early IgA nephropathy |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
8 |
Experiment ID |
196 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Alix|TSG101|HSP70
|
EV Cytosolic markers |
✔
CD9
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
22418980
|
Organism |
Homo sapiens |
Experiment description |
A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
Authors |
Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
Journal name |
Kidney Int
|
Publication year |
2012 |
Sample |
Urine |
Sample name |
Urine - Normal high density |
Isolation/purification methods |
Differential centrifugation Sucrose cushion |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
9 |
Experiment ID |
197 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Alix|TSG101|HSP70
|
EV Cytosolic markers |
✔
CD9
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
22418980
|
Organism |
Homo sapiens |
Experiment description |
A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
Authors |
Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
Journal name |
Kidney Int
|
Publication year |
2012 |
Sample |
Urine |
Sample name |
Urine - Normal low density |
Isolation/purification methods |
Differential centrifugation Sucrose cushion |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
Protein-protein interactions for CPM |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which CPM is involved |
No pathways found
|
|
|