Gene description for Uso1
Gene name USO1 vesicle docking factor
Gene symbol Uso1
Other names/aliases 115kDa
Species Mus musculus
 Database cross references - Uso1
ExoCarta ExoCarta_56041
Entrez Gene 56041
UniProt Q9Z1Z0  
 Uso1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Uso1
Molecular Function
    protein transporter activity GO:0008565 IDA
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    vesicle-mediated transport GO:0016192 IEA
    vesicle fusion with Golgi apparatus GO:0048280 IEA
    intracellular protein transport GO:0006886 IDA
    Golgi vesicle docking GO:0048211 IBA
    transcytosis GO:0045056 ISO
    membrane fusion GO:0061025 ISO
    ER to Golgi vesicle-mediated transport GO:0006888 IBA
    protein transport GO:0015031 IEA
    transport GO:0006810 IEA
    Golgi vesicle transport GO:0048193 IEA
Subcellular Localization
    ER to Golgi transport vesicle membrane GO:0012507 IBA
    Golgi membrane GO:0000139 IEA
    Golgi stack GO:0005795 IBA
    nucleolus GO:0005730 ISO
    cytosol GO:0005829 IDA
    cytoplasm GO:0005737 IEA
    Golgi apparatus GO:0005794 ISO
    perinuclear region of cytoplasm GO:0048471 IDA
    membrane GO:0016020 ISO
    endoplasmic reticulum GO:0005783 IBA
 Experiment description of studies that identified Uso1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Uso1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Uso1 is involved
Golgi Cisternae Pericentriolar Stack Reorganization IEA Reactome

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