Gene description for SLC35E1
Gene name solute carrier family 35, member E1
Gene symbol SLC35E1
Other names/aliases -
Species Homo sapiens
 Database cross references - SLC35E1
ExoCarta ExoCarta_79939
Vesiclepedia VP_79939
Entrez Gene 79939
HGNC 20803
UniProt Q96K37  
 SLC35E1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for SLC35E1
Molecular Function
    protein binding GO:0005515 IPI
    antiporter activity GO:0015297 IBA
Biological Process
    transmembrane transport GO:0055085 IBA
Subcellular Localization
    Golgi apparatus GO:0005794 IBA
    Golgi apparatus GO:0005794 IDA
    membrane GO:0016020 IEA
 Experiment description of studies that identified SLC35E1 in exosomes
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for SLC35E1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Csnk1d  
Affinity Capture-MS Mus musculus
2 MPP1 4354
Two-hybrid Homo sapiens
3 SGCA  
Affinity Capture-MS Homo sapiens
4 GJD3  
Proximity Label-MS Homo sapiens
5 Tmed2 56334
Affinity Capture-MS Mus musculus
6 GJB2  
Affinity Capture-MS Homo sapiens
7 RAMP2  
Affinity Capture-MS Homo sapiens
8 Bap1  
Affinity Capture-MS Mus musculus
9 KLRB1  
Affinity Capture-MS Homo sapiens
10 RAB1A 5861
Affinity Capture-MS Homo sapiens
11 AIFM1 9131
Affinity Capture-MS Homo sapiens
12 TMEM63B 55362
Affinity Capture-MS Homo sapiens
13 GOSR1 9527
Affinity Capture-MS Homo sapiens
14 RAMP3  
Affinity Capture-MS Homo sapiens
15 EXOSC9 5393
Affinity Capture-MS Homo sapiens
16 BSG 682
Affinity Capture-MS Homo sapiens
17 Cct3 12462
Affinity Capture-MS Mus musculus
18 MGARP  
Affinity Capture-MS Homo sapiens
19 Atp2a2 11938
Affinity Capture-MS Mus musculus
20 MBOAT1  
Affinity Capture-MS Homo sapiens
21 CHIA  
Affinity Capture-MS Homo sapiens
22 FXYD6  
Two-hybrid Homo sapiens
23 MCOLN1 57192
Two-hybrid Homo sapiens
24 KIF2A 3796
Affinity Capture-MS Homo sapiens
25 CLPP 8192
Proximity Label-MS Homo sapiens
26 AQP3  
Affinity Capture-MS Homo sapiens
27 MFSD4  
Affinity Capture-MS Homo sapiens
28 Rab5c 19345
Affinity Capture-MS Mus musculus
29 DDX58 23586
Affinity Capture-RNA Homo sapiens
30 RIPK4  
Affinity Capture-MS Homo sapiens
31 KLRD1  
Affinity Capture-MS Homo sapiens
32 GCNT2 2651
Affinity Capture-MS Homo sapiens
33 Sec24c  
Affinity Capture-MS Mus musculus
34 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
35 TM9SF3 56889
Affinity Capture-MS Homo sapiens
36 ALPI  
Affinity Capture-MS Homo sapiens
37 IFT52 51098
Affinity Capture-MS Homo sapiens
38 ARMC6 93436
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 Tgfbr1 21812
Affinity Capture-MS Mus musculus
40 TSPAN8 7103
Affinity Capture-MS Homo sapiens
41 Kcnk1  
Affinity Capture-MS Mus musculus
42 Uso1 56041
Affinity Capture-MS Mus musculus
43 NAAA  
Affinity Capture-MS Homo sapiens
44 RAB7A 7879
Proximity Label-MS Homo sapiens
45 HLA-B 3106
Affinity Capture-MS Homo sapiens
46 GPR182  
Affinity Capture-MS Homo sapiens
47 FAM46A  
Affinity Capture-MS Homo sapiens
48 CHST15 51363
Affinity Capture-MS Homo sapiens
49 TMEM165 55858
Affinity Capture-MS Homo sapiens
50 VIPR1  
Affinity Capture-MS Homo sapiens
51 RAB5C 5878
Affinity Capture-MS Homo sapiens
52 C9orf72  
Affinity Capture-MS Homo sapiens
53 FTHL17  
Two-hybrid Homo sapiens
54 HECW2  
Affinity Capture-MS Homo sapiens
55 ATP2A3 489
Affinity Capture-MS Homo sapiens
56 GORASP2 26003
Affinity Capture-MS Homo sapiens
57 Smn1 20595
Affinity Capture-MS Mus musculus
58 Magoh  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which SLC35E1 is involved
No pathways found





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