Gene description for GOSR1
Gene name golgi SNAP receptor complex member 1
Gene symbol GOSR1
Other names/aliases GOLIM2
GOS-28
GOS28
GOS28/P28
GS28
P28
Species Homo sapiens
 Database cross references - GOSR1
ExoCarta ExoCarta_9527
Entrez Gene 9527
HGNC 4430
MIM 604026
UniProt O95249  
 GOSR1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Thymus 23844026    
 Gene ontology annotations for GOSR1
Molecular Function
    SNAP receptor activity GO:0005484 IDA
Biological Process
    membrane fusion GO:0061025 IDA
    protein transport GO:0015031 IEA
    ER to Golgi vesicle-mediated transport GO:0006888 IEA
    intra-Golgi vesicle-mediated transport GO:0006891 TAS
    retrograde transport, endosome to Golgi GO:0042147 IDA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    SNARE complex GO:0031201 TAS
    cis-Golgi network GO:0005801 IEA
    Golgi apparatus GO:0005794 IDA
    membrane GO:0016020 IDA
    Golgi membrane GO:0000139 IDA
 Experiment description of studies that identified GOSR1 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GOSR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IL27RA 9466
Affinity Capture-Western Homo sapiens
2 BET1  
Affinity Capture-Western Homo sapiens
3 EBI3  
Affinity Capture-Western Homo sapiens
4 BET1L  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
5 YKT6 10652
Affinity Capture-Western Homo sapiens
6 STX5A  
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
7 SNAP25 6616
Reconstituted Complex Homo sapiens
8 NSF 4905
Invivo Homo sapiens
9 USO1 8615
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
10 NAPA 8775
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GOSR1 is involved
No pathways found





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