Gene description for KRTCAP3
Gene name keratinocyte associated protein 3
Gene symbol KRTCAP3
Other names/aliases KCP3
MRV222
PRO9898
Species Homo sapiens
 Database cross references - KRTCAP3
ExoCarta ExoCarta_200634
Vesiclepedia VP_200634
Entrez Gene 200634
HGNC 28943
UniProt Q53RY4  
 KRTCAP3 identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells 34887515    
 Gene ontology annotations for KRTCAP3
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified KRTCAP3 in sEVs
1
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
 Protein-protein interactions for KRTCAP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 REEP5 7905
Affinity Capture-MS Homo sapiens
2 SMCR8 140775
Affinity Capture-MS Homo sapiens
3 FNDC9  
Two-hybrid Homo sapiens
4 FZD2 2535
Affinity Capture-MS Homo sapiens
5 TTYH3 80727
Affinity Capture-MS Homo sapiens
6 FITM2  
Affinity Capture-MS Homo sapiens
7 MSMO1 6307
Affinity Capture-MS Homo sapiens
8 KIAA2013 90231
Affinity Capture-MS Homo sapiens
9 CD47 961
Affinity Capture-MS Homo sapiens
10 ATP12A 479
Affinity Capture-MS Homo sapiens
11 VAMP3 9341
Affinity Capture-MS Homo sapiens
12 TSPAN15 23555
Affinity Capture-MS Homo sapiens
13 GOLPH3 64083
Affinity Capture-MS Homo sapiens
14 FUT8 2530
Affinity Capture-MS Homo sapiens
15 TMEM186  
Affinity Capture-MS Homo sapiens
16 MFSD8 256471
Affinity Capture-MS Homo sapiens
17 ADGRL3 23284
Affinity Capture-MS Homo sapiens
18 KLRG2 346689
Affinity Capture-MS Homo sapiens
19 GOSR2 9570
Affinity Capture-MS Homo sapiens
20 GOLPH3L 55204
Affinity Capture-MS Homo sapiens
21 SLC22A23  
Affinity Capture-MS Homo sapiens
22 WDR41  
Affinity Capture-MS Homo sapiens
23 GOLGA5 9950
Affinity Capture-MS Homo sapiens
24 ZDHHC18 84243
Affinity Capture-MS Homo sapiens
25 MEOX2  
Two-hybrid Homo sapiens
26 ATP6V0A2 23545
Affinity Capture-MS Homo sapiens
27 GOSR1 9527
Affinity Capture-MS Homo sapiens
28 TMX4 56255
Affinity Capture-MS Homo sapiens
29 GPRC5B 51704
Affinity Capture-MS Homo sapiens
30 ZDHHC13 54503
Affinity Capture-MS Homo sapiens
31 REEP6  
Affinity Capture-MS Homo sapiens
32 TSPAN3 10099
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KRTCAP3 is involved
No pathways found





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