Experiment description of studies that identified KLRG2 in exosomes

1 Experiment ID 363 MISEV standards ✘ Biophysical techniques ✔ TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1 Enriched markers ✔ DCLK1 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 364 MISEV standards ✘ Biophysical techniques ✔ TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1 Enriched markers ✔ DCLK1 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

3 Experiment ID 365 MISEV standards ✘ Biophysical techniques ✔ TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1 Enriched markers ✔ DCLK1 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33991177     Organism Homo sapiens Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." Journal name Proteomics Publication year 2021 Sample Gastric cancer cells Sample name MKN1 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

4 Experiment ID 211 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ cytochrome c|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

5 Experiment ID 212 MISEV standards ✔ CEM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ Cytochrome C|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for KLRG2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ZNF185 7739 Affinity Capture-MS Homo sapiens 2 ST6GALNAC4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 ST8SIA3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 PPP3CA 5530 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 ORC4   Affinity Capture-MS Homo sapiens 6 CHRNA4   Affinity Capture-MS Homo sapiens 7 OCLN 100506658 Affinity Capture-MS Homo sapiens 8 F5 2153 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 CD8B 926 Affinity Capture-MS Homo sapiens 10 NOP9 161424 Affinity Capture-MS Homo sapiens 11 BOLA2B 654483 Affinity Capture-MS Homo sapiens 12 STK39 27347 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 CD47 961 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 ITIH2 3698 Affinity Capture-MS Homo sapiens 15 GPR114   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 16 ST6GALNAC3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 ITFG1 81533 Affinity Capture-MS Homo sapiens 18 ZDHHC6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 C11orf87   Affinity Capture-MS Homo sapiens 20 USO1 8615 Affinity Capture-MS Homo sapiens 21 LPGAT1 9926 Affinity Capture-MS Homo sapiens 22 FAM171A2 284069 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 PPP3CB   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 C3orf62   Affinity Capture-MS Homo sapiens 25 VWA1 64856 Affinity Capture-MS Homo sapiens 26 LRRC4B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 SFXN2   Affinity Capture-MS Homo sapiens 28 TMEM192 201931 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 TNFSF9   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 LRFN1   Affinity Capture-MS Homo sapiens 31 PIGG   Affinity Capture-MS Homo sapiens 32 GXYLT2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 PPP3R1 5534 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 ADCK4 79934 Affinity Capture-MS Homo sapiens 35 TBC1D17 79735 Affinity Capture-MS Homo sapiens 36 RPS4Y2 140032 Affinity Capture-MS Homo sapiens 37 AURKA 6790 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 MANSC1 54682 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 TOR1B 27348 Affinity Capture-MS Homo sapiens 40 PCDHB6   Affinity Capture-MS Homo sapiens 41 AVPR1B   Affinity Capture-MS Homo sapiens 42 KRTCAP3 200634 Affinity Capture-MS Homo sapiens 43 PMAIP1   Affinity Capture-MS Homo sapiens 44 PTCD2   Affinity Capture-MS Homo sapiens 45 INTS7   Affinity Capture-MS Homo sapiens 46 WNT5A 7474 Affinity Capture-MS Homo sapiens 47 IL27RA 9466 Affinity Capture-MS Homo sapiens 48 IPPK   Affinity Capture-MS Homo sapiens 49 FGFRL1 53834 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 HLA-DPA1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 51 EPHB4 2050 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 ABCB7 22 Affinity Capture-MS Homo sapiens 53 CLRN2   Affinity Capture-MS Homo sapiens 54 PCDHA8   Affinity Capture-MS Homo sapiens 55 FAM189B   Affinity Capture-MS Homo sapiens 56 FNDC3B 64778 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 TMEM30A 55754 Affinity Capture-MS Homo sapiens 58 EMILIN3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 59 TNKS 8658 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 60 MSMO1 6307 Affinity Capture-MS Homo sapiens 61 SMIM5   Affinity Capture-MS Homo sapiens 62 CNTNAP1 8506 Affinity Capture-MS Homo sapiens 63 LPCAT4   Affinity Capture-MS Homo sapiens 64 POM121   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 EGFL7 51162 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 HTR2C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 67 FRMD5 84978 Affinity Capture-MS Homo sapiens 68 TMEM74   Affinity Capture-MS Homo sapiens 69 DOLK 22845 Affinity Capture-MS Homo sapiens 70 ZDHHC18 84243 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 71 PRSS8 5652 Affinity Capture-MS Homo sapiens 72 PCDHA12   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 73 LTBP1 4052 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 74 STBD1 8987 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 75 B3GAT3 26229 Affinity Capture-MS Homo sapiens 76 WNT11 7481 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 77 HSPA9 3313 Affinity Capture-MS Homo sapiens 78 UBXN1 51035 Affinity Capture-MS Homo sapiens 79 TSPAN10 83882 Affinity Capture-MS Homo sapiens 80 HS3ST1   Affinity Capture-MS Homo sapiens 81 PRKCSH 5589 Affinity Capture-MS Homo sapiens 82 COLEC12 81035 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 83 SIDT2 51092 Affinity Capture-MS Homo sapiens 84 EPHA4 2043 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 85 UBA52 7311 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 86 TMEM30B 161291 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 87 PCDHA7   Affinity Capture-MS Homo sapiens 88 EPHB1 2047 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 89 UBE3C 9690 Affinity Capture-MS Homo sapiens 90 LPCAT2 54947 Affinity Capture-MS Homo sapiens 91 PTPRS 5802 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 92 WNT5B 81029 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 93 APBA2 321 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 94 AGPAT6 137964 Affinity Capture-MS Homo sapiens 95 GLRX3 10539 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 96 LOC100507703   Affinity Capture-MS Homo sapiens 97 ALG11   Affinity Capture-MS Homo sapiens 98 PRSS23 11098 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 99 TIMP3 7078 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 100 PPP3CC 5533 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 101 HLA-C 3107 Affinity Capture-MS Homo sapiens View the network

Pathways in which KLRG2 is involved

No pathways found