Gene description for STK39
Gene name serine threonine kinase 39
Gene symbol STK39
Other names/aliases DCHT
Species Homo sapiens
 Database cross references - STK39
ExoCarta ExoCarta_27347
Entrez Gene 27347
HGNC 17717
MIM 607648
UniProt Q9UEW8  
 STK39 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for STK39
Molecular Function
    ATP binding GO:0005524 IEA
    protein serine/threonine kinase activity GO:0004674 IDA
    protein kinase binding GO:0019901 IEA
    protein binding GO:0005515 IPI
    receptor signaling protein serine/threonine kinase activity GO:0004702 NAS
Biological Process
    peptidyl-serine phosphorylation GO:0018105 IDA
    response to stress GO:0006950 NAS
    positive regulation of potassium ion transport GO:0043268 IEA
    negative regulation of potassium ion transmembrane transporter activity GO:1901017 IDA
    stress-activated protein kinase signaling cascade GO:0031098 IBA
    activation of protein kinase activity GO:0032147 IBA
    negative regulation of potassium ion transmembrane transport GO:1901380 IDA
    peptidyl-threonine phosphorylation GO:0018107 IDA
    protein phosphorylation GO:0006468 NAS
    regulation of inflammatory response GO:0050727 IEA
    cellular hypotonic response GO:0071476 IC
    negative regulation of rubidium ion transmembrane transporter activity GO:2000687 IDA
    regulation of apoptotic process GO:0042981 IBA
    signal transduction by protein phosphorylation GO:0023014 IDA
    regulation of mitotic cell cycle GO:0007346 IBA
    intracellular signal transduction GO:0035556 IDA
    negative regulation of rubidium ion transport GO:2000681 IDA
Subcellular Localization
    cytoplasm GO:0005737 NAS
    nucleus GO:0005634 NAS
    cytoskeleton GO:0005856 IEA
    basolateral plasma membrane GO:0016323 IEA
    apical plasma membrane GO:0016324 IEA
 Experiment description of studies that identified STK39 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for STK39
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MBP  
Biochemical Activity Homo sapiens
2 GSN 2934
Two-hybrid Homo sapiens
3 WNK4  
Two-hybrid Homo sapiens
4 MAPK14 1432
Affinity Capture-Western Homo sapiens
5 STK39 27347
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
6 AATK  
Two-hybrid Homo sapiens
7 HSPH1 10808
Two-hybrid Homo sapiens
8 OTOF  
Two-hybrid Homo sapiens
9 SLC12A2 6558
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which STK39 is involved
No pathways found

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